Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.55 |
| ▸ | MAOA | P21397 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | TOP2A | P11388 | 2/20 | 0.50 |
| ▸ | CTH | P32929 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodomethane SCHEMBL3170391 | 1.00 | NR4A1 (0.55) | NR4A1MAOANPC1RAB9AMEN1 | |
| SCHEMBL103202 | 0.94 | — | — | |
| SCHEMBL333460 | 0.94 | — | — | |
| SCHEMBL103201 | 0.94 | — | — | |
| Chloromethane SCHEMBL1169195 | 0.92 | NR4A1 (0.55) | NR4A1MAOANPC1RAB9AMEN1 | |
| Chloromethane SCHEMBL1168289 | 0.92 | NR4A1 (0.55) | NR4A1MAOANPC1RAB9AMEN1 | |
| Hydrochloric Acid SCHEMBL10825098 | 0.92 | NR4A1 (0.59) | NR4A1MAOANPC1RAB9AMEN1 | |
| SCHEMBL3889364 | 0.92 | NR4A1 (0.59) | NR4A1MAOANPC1RAB9AMEN1 | |
| SCHEMBL30800889 | 0.92 | NR4A1 (0.59) | NR4A1MAOANPC1RAB9AMEN1 | |
| SCHEMBL29119568 | 0.92 | NR4A1 (0.59) | NR4A1MAOANPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1344 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110536699-A | Passive antibody-dependent cell-mediated activation | OHIO STATE INNOVATION FOUNDATION | 2019-12-03 | — | — | CN | claimed |
| CN-110536703-A | Use Anti-AXL antibodies-drug conjugate combination treatment | ADC THERAPEUTICS SA | 2019-12-03 | — | — | CN | claimed |
| CN-110520156-A | Method for immunomodulation against foreign antigens and/or autoantigens | TANG ZEQUN | 2019-11-29 | — | — | CN | claimed |
| CN-110520539-A | The method for predicting the clinical effectiveness of anticarcinogen | MITRA RXDX INC | 2019-11-29 | — | — | CN | claimed |
| CN-110505877-A | RNA cancer vaccine | MODERNATX INC | 2019-11-26 | — | — | CN | claimed |
| CN-110505882-A | Compositions and methods for treating cancer with a combination of an antagonist of PD-1 and an anti-CTLA 4 antibody | MERCK SHARP & DOHME | 2019-11-26 | — | — | CN | claimed |
| CN-110494137-A | Mammality rapamycin target protein inhibitor and chloroquine are in the purposes for the treatment of cancer | JOHNPRO BIOTECH INC | 2019-11-22 | — | — | CN | claimed |
| CN-110494155-A | For improving immunocompetent TGF β and ActRII antagonist | ACCELERON PHARMA INC | 2019-11-22 | — | — | CN | claimed |
| CN-110494565-A | It is engineered B cell and compositions related and method | JUNO THERAPEUTICS INC | 2019-11-22 | — | — | CN | claimed |
| CN-110461417-A | Dosing regimen of ceritinib and anti-PD-1 antibody molecule combination | NOVARTIS AG | 2019-11-15 | — | — | CN | claimed |
| CN-105979971-A | Antibody-drug conjugates and immunotoxins | 欧寇玛特瑞克斯生物制药公司 | 2016-09-28 | — | — | CN | claimed |
| CN-105980411-A | Antibody-drug conjugates and immunotoxins | 欧寇玛特瑞克斯生物制药公司 | 2016-09-28 | — | — | CN | claimed |
| CN-105793260-A | 1- (5-tert-butyl-2-aryl-pyrazol-3-yl) -3- [ 2-fluoro-4- [ (3-oxo-4H-pyrido [2, 3-B ] pyrazin-8-yl) oxy ] phenyl ] urea derivatives as RAF inhibitors for the treatment of cancer | 癌症研究技术有限公司 | 2016-07-20 | — | — | CN | claimed |
| CN-105473581-A | Novel substituted bicyclic compounds as bromodomain inhibitors | ZENITH EPIGENETICS CORP | 2016-04-06 | — | — | CN | claimed |
| US-20100022010-A1 | CHEMICAL AGENT DETECTION METHOD AND APPARATUS | CHEMMOTIF INC. (US) | 2010-01-28 | — | — | US | claimed |
| CN-101623499-A | Medical composition of antibiotic and pidotimod as well as preparation method and medical application thereof | XIHONG YANG | 2010-01-13 | — | — | CN | claimed |
| EP-1913399-A4 | CHEMICAL WARFARE AGENT (CWA) AND TOXIC INDUSTRIAL CHEMICAL (TIC) DETECTION BY DEGRADATION COMBINED WITH ACID-BASE INDICATOR DYES | CHEMMOTIF INC (US) | 2009-05-06 | — | — | EP | claimed |
| EP-1913399-A2 | CHEMICAL WARFARE AGENT (CWA) AND TOXIC INDUSTRIAL CHEMICAL (TIC) DETECTION BY DEGRADATION COMBINED WITH ACID-BASE INDICATOR DYES | Chemmotif, Inc. (US) | 2008-04-23 | — | — | EP | claimed |
| WO-2008018853-A2 | CHEMICAL WARFARE AGENT (CWA) AND TOXIC INDUSTRIAL CHEMICAL (TIC) DETECTION BY DEGRADATION COMBINED WITH ACID-BASE INDICATOR DYES | CHEMMOTIF, INC. (US) | 2008-02-14 | — | — | WO | claimed |
| US-6166032-A | Method for controlling tobacco use and alleviating withdrawal symptoms due to cessation of tobacco use | SYNAPSE PHARMACEUTICALS INTERNATIONAL, INC. (CA) | 2000-12-26 | — | — | US | claimed |