Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 14/20 | 0.62 |
| ▸ | TTR | P02766 | 2/20 | 0.50 |
| ▸ | RBP4 | P02753 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17803769 | 0.89 | SCD (0.47) | SCD | |
| SCHEMBL3338132 | 0.86 | SCD (0.59) | SCDTTRRBP4 | |
| SCHEMBL3336680 | 0.82 | SCD (0.70) | SCD | |
| SCHEMBL3339785 | 0.77 | SCD (1.00) | SCDTTRRBP4 | |
| SCHEMBL13301823 | 0.76 | SCD (0.80) | SCDTTRRBP4 | |
| SCHEMBL3342320 | 0.76 | SCD (0.80) | SCDTTRRBP4 | |
| SCHEMBL3336891 | 0.76 | SCD (0.79) | SCDTTRRBP4 | |
| SCHEMBL14870437 | 0.75 | SCD (0.47) | SCDTTRRBP4 | |
| SCHEMBL3335406 | 0.75 | SCD (0.77) | SCDTTRRBP4 | |
| SCHEMBL4515605 | 0.75 | SCD (1.00) | SCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9358250-B2 | Methods of using SCD1 antagonists | GENENTECH, INC. (US) | 2016-06-07 | — | — | US | disclosed |
| US-20100152208-A1 | BICYCLIC HETEROAROMATIC COMPOUNDS AS INHIBITORS OF STEAROYL-COENZYME A DELTA-9 DESATURASE | MERCK FROSST CANADA LTD. | 2010-06-17 | — | — | US | disclosed |
| US-20100152208-A1 | BICYCLIC HETEROAROMATIC COMPOUNDS AS INHIBITORS OF STEAROYL-COENZYME A DELTA-9 DESATURASE | MERCK FROSST CANADA LTD. | 2010-06-17 | — | — | US | disclosed |
| US-20100152208-A1 | BICYCLIC HETEROAROMATIC COMPOUNDS AS INHIBITORS OF STEAROYL-COENZYME A DELTA-9 DESATURASE | MERCK FROSST CANADA LTD. | 2010-06-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152208-A1 | BICYCLIC HETEROAROMATIC COMPOUNDS AS INHIBITORS OF STEAROYL-COENZYME A DELTA-9 DESATURASE | SCD, SCD5, CPT1A | SCD 1/4885TTR 3454/4885RBP4 866/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.