Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3336812 | 0.83 | KMT2A (0.52) | TSHRSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL13581 | 0.83 | EPHX1 (0.55) | EPHX1TSHRCA12CA1CA2 | |
| SCHEMBL19652274 | 0.83 | EPHX1 (0.55) | EPHX1TSHRCA12CA1CA2 | |
| SCHEMBL12026402 | 0.81 | EPHX1 (0.52) | EPHX1TSHRCA12CA1CA2 | |
| SCHEMBL4432505 | 0.80 | L3MBTL1 (0.40) | EPHX1ALDH1A1L3MBTL1KMT2ATDP1 | |
| SCHEMBL15199665 | 0.77 | EPHX1 (0.47) | EPHX1TSHRCA12CA1CA2 | |
| SCHEMBL27770664 | 0.76 | EPHX1 (0.52) | EPHX1TSHRCA12CA1CA2 | |
| SCHEMBL3220227 | 0.76 | EPHX1 (0.52) | EPHX1TSHRCA12CA1CA2 | |
| SCHEMBL9779 | 0.73 | TDP1 (0.53) | EPHX1TSHRCA12CA1CA2 | |
| SCHEMBL3224826 | 0.73 | TSHR (0.49) | EPHX1TSHRCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100145057-A1 | NOVEL PRODRUGS | SUN PHARMA ADVANCED RESEARCH COMPANY LTD. (IN) | 2010-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100145057-A1 | NOVEL PRODRUGS | UGT2B7, UGT1A1, UGT1A6 | EPHX1 350/4885TSHR 3135/4885CA12 693/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.