Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | ADH1B | P00325 | 1/20 | 0.39 |
| ▸ | ADH1C | P00326 | 1/20 | 0.39 |
| ▸ | ADH1A | P07327 | 1/20 | 0.39 |
| ▸ | ADH4 | P08319 | 1/20 | 0.39 |
| ▸ | ADH7 | P40394 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | EP300 | Q09472 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL223057 | 1.00 | TSHR (0.44) | TSHRTHRBFAAHTRPV1ADH1B | |
| SCHEMBL7389147 | 1.00 | TSHR (0.44) | TSHRTHRBFAAHTRPV1ADH1B | |
| SCHEMBL3855699 | 1.00 | TSHR (0.44) | TSHRTHRBFAAHTRPV1ADH1B | |
| SCHEMBL9784627 | 1.00 | TSHR (0.44) | TSHRTHRBFAAHTRPV1ADH1B | |
| SCHEMBL1931465 | 1.00 | TSHR (0.44) | TSHRTHRBFAAHTRPV1ADH1B | |
| SCHEMBL9216022 | 1.00 | TSHR (0.44) | TSHRTHRBFAAHTRPV1ADH1B | |
| SCHEMBL9205173 | 1.00 | TSHR (0.44) | TSHRTHRBFAAHTRPV1ADH1B | |
| SCHEMBL6242253 | 1.00 | TSHR (0.44) | TSHRTHRBFAAHTRPV1ADH1B | |
| SCHEMBL183454 | 0.97 | TSHR (0.40) | TSHRTHRBFAAHTRPV1ADH1B | |
| SCHEMBL333838 | 0.90 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6133466-A | BINDERS IN PAINTS AND VARNISHES | DEGUSSA-HUELS AKTIENGESELLSCHAFT (DE) | 2000-10-17 | — | — | US | claimed |
| US-20210324287-A1 | LUBRICANT COMPOSITION | KLUEBER LUBRICATION MUENCHEN SE & CO. KG (DE) | 2021-10-21 | — | — | US | disclosed |
| US-11085004-B2 | Lubricant composition | KLUEBER LUBRICATION MUENCHEN SE & CO. KG (DE) | 2021-08-10 | — | — | US | disclosed |
| US-20200157454-A1 | LUBRICANT COMPOSITION | KLUEBER LUBRICATION MUENCHEN SE & CO. KG (DE) | 2020-05-21 | — | — | US | disclosed |
| CN-103619987-B | Color converter | 巴斯夫欧洲公司 | 2016-11-16 | — | — | CN | disclosed |
| US-20100143273-A1 | COSMETIC COMPOSITION COMPRISING AT LEAST ONE APROTIC HYDROCARBON-BASED VOLATILE SOLVENT | L'OREAL S.A. (FR) | 2010-06-10 | — | — | US | disclosed |
| EP-2083789-A1 | COSMETIC COMPOSITION COMPRISING AT LEAST ONE APROTIC HYDROCARBON-BASED VOLATILE SOLVENT | L'Oréal (FR) | 2009-08-05 | — | — | EP | disclosed |
| WO-2008061985-A1 | COSMETIC COMPOSITION COMPRISING AT LEAST ONE APROTIC HYDROCARBON-BASED VOLATILE SOLVENT | L'OREAL (FR) | 2008-05-29 | — | — | WO | disclosed |
| US-5494973-A | PREPARING ELASTOMER LATEX IN AN AQUEOUS EMULSION IN THE PRESENCE OF AN ETHYLENICALLY UNSATURATED MONOMER AND AN IONIC SURFACTANT, ADDING VINYL MONOMER AND TRANSFER AGENT HAVING CHARGE OPPOSITE TO THAT OF THE IONIC SURFACTANT, POLYMERIZING | ELF ATOCHEM S.A. (FR) | 1996-02-27 | — | — | US | disclosed |
| EP-0651643-A4 | 17-ALKYLKETONE STEROIDS USEFUL AS 5--g(a)-REDUCTASE INHIBITORS. | SMITHKLINE BEECHAM CORP (US) | 1995-10-04 | — | — | EP | disclosed |
| EP-0651643-A1 | 17-ALKYLKETONE STEROIDS USEFUL AS 5-$g(a)-REDUCTASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-05-10 | — | — | EP | disclosed |
| WO-1994000125-A1 | 17-ALKYLKETONE STEROIDS USEFUL AS 5-α-REDUCTASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1994-01-06 | — | — | WO | disclosed |
| US-4569940-A | Certain 5-N-mono- or disubstituted sulfamoyl benzamides having use in treatment of emesis, impaired gastro-intestinal motility disorders and central nervous system disorders | BEECHAM GROUP P.L.C. (GB) | 1986-02-11 | — | — | US | disclosed |
| EP-0096524-A2 | Bicyclic benzamides or anilides, process for their preparation, and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1983-12-21 | — | — | EP | disclosed |