SCHEMBL3335931

SCHEMBL3335931

COC(=O)C1NC(=O)C1Cc1ccnc(N(OC(C)(C)C)C(=O)OC(C)(C)C)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3336555 0.90 AAK1 (0.30)
SCHEMBL3338226 0.90 AAK1 (0.30)
SCHEMBL13302748 0.89 SYK (0.36)
SCHEMBL3335928 0.89 SYK (0.36)
SCHEMBL3336545 0.79 SYK (0.35)
SCHEMBL3338219 0.79 SYK (0.35)
SCHEMBL13899711 0.77 L3MBTL1 (0.37)
SCHEMBL13302752 0.77 L3MBTL1 (0.37)
SCHEMBL3336431 0.77 L3MBTL1 (0.37)
SCHEMBL3336429 0.77 L3MBTL1 (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100144698-A1 SUBSTITUTED AZETIDINONES DAIAMED (US) 2010-06-10 US disclosed
US-20090143351-A1 SUBSTITUTED AZETIDINONES DAIAMED (US) 2009-06-04 US disclosed
US-7501404-B2 Substituted azetidinones DAIMED (US) 2009-03-10 US disclosed
EP-1871741-A2 SUBSTITUTED AZETIDINONES Daiamed, Inc. (US) 2008-01-02 EP disclosed
US-20070105832-A1 Substituted azetidinones Cadrenal Therapeutics, Inc. 2007-05-10 US disclosed
WO-2006108039-A2 SUBSTITUTED AZETIDINONES DAIAMED, INC. (US) 2006-10-12 WO disclosed