Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1229549 | 0.96 | TSHR (0.33) | TSHRCYP3A4NFKB1NPSR1CA2 | |
| SCHEMBL124997 | 0.91 | CYP3A4 (0.39) | TSHRCYP3A4NFKB1NPSR1CA2 | |
| Acetoacetic Acid SCHEMBL1081472 | 0.88 | CA4 (0.35) | TSHRCYP3A4NFKB1NPSR1CA2 | |
| SCHEMBL17968609 | 0.86 | CYP3A4 (0.39) | TSHRCYP3A4NFKB1NPSR1CA2 | |
| SCHEMBL21519878 | 0.86 | CYP3A4 (0.39) | TSHRCYP3A4NFKB1NPSR1CA2 | |
| SCHEMBL21219167 | 0.86 | CYP3A4 (0.39) | TSHRCYP3A4NFKB1NPSR1CA2 | |
| SCHEMBL21219173 | 0.86 | CYP3A4 (0.39) | TSHRCYP3A4NFKB1NPSR1CA2 | |
| SCHEMBL21219181 | 0.86 | CYP3A4 (0.39) | TSHRCYP3A4NFKB1NPSR1CA2 | |
| SCHEMBL21219179 | 0.86 | CYP3A4 (0.39) | TSHRCYP3A4NFKB1NPSR1CA2 | |
| SCHEMBL10415391 | 0.86 | CYP3A4 (0.39) | TSHRCYP3A4NFKB1NPSR1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8563675-B2 | Curable compositions composed of silanes with two hydrolyzable groups | HENKEL AG & CO. KGAA (DE) | 2013-10-22 | — | — | US | disclosed |
| US-20100204387-A1 | CURABLE COMPOSITIONS COMPOSED OF SILANES WITH TWO HYDROLYZABLE GROUPS | HENKEL AG & CO. KGAA (DE) | 2010-08-12 | — | — | US | disclosed |
| US-20100143712-A1 | SILANE-CROSSLINKING ADHESIVE OR SEALANT COMPRISING N-SILYLALKYLAMIDES AND USE THEREOF | HENKEL AG & CO. KGAA (DE) | 2010-06-10 | — | — | US | disclosed |