Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10077671 | 1.00 | CXCR2 (0.66) | CXCR2CX3CR1 | |
| SCHEMBL333754 | 1.00 | CXCR2 (0.66) | CXCR2CX3CR1 | |
| SCHEMBL333755 | 1.00 | CXCR2 (0.66) | CXCR2CX3CR1 | |
| SCHEMBL334117 | 0.90 | CXCR2 (0.69) | CXCR2CX3CR1 | |
| SCHEMBL10084131 | 0.88 | CXCR2 (0.71) | CXCR2CX3CR1 | |
| SCHEMBL334864 | 0.85 | CXCR2 (0.69) | CXCR2CX3CR1 | |
| SCHEMBL10077669 | 0.85 | CXCR2 (0.69) | CXCR2CX3CR1 | |
| SCHEMBL334358 | 0.83 | CXCR2 (0.66) | CXCR2CX3CR1 | |
| SCHEMBL10077644 | 0.83 | CXCR2 (0.66) | CXCR2CX3CR1 | |
| SCHEMBL335013 | 0.82 | CXCR2 (0.63) | CXCR2CX3CR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090298810-A1 | IL-8 Receptor Antagonists | SMITHKLINE BEECHAM CORPORATION | 2009-12-03 | — | — | US | claimed |
| US-8097626-B2 | IL-8 receptor antagonists | GLAXOSMITHKLINE LLC (US) | 2012-01-17 | — | — | US | disclosed |
| US-20090298810-A1 | IL-8 Receptor Antagonists | SMITHKLINE BEECHAM CORPORATION | 2009-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090298810-A1 | IL-8 Receptor Antagonists | CXCL8, CCR8, IL1RN | CXCR2 6/4885CX3CR1 37/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.