SCHEMBL3337772

SCHEMBL3337772

CN1CC=C(c2cn(S(=O)(=O)c3ccc(N(C)C)cc3)c3ccc(C(F)(F)F)cc23)CC1

nearest known ligand 0.60

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 13/20 0.60
SCN9A Q15858 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL4674531 0.90 HTR6 (0.64) HTR6SCN9A
SCHEMBL4676869 0.90 HTR6 (0.64) HTR6SCN9A
SCHEMBL3343253 0.90 HTR6 (0.55) HTR6SCN9A
SCHEMBL3343726 0.90 HTR6 (0.59) HTR6SCN9A
SCHEMBL4676433 0.89 HTR6 (0.63) HTR6SCN9A
Hydrochloric Acid SCHEMBL4674835 0.89 HTR6 (0.63) HTR6SCN9A
Hydrochloric Acid SCHEMBL4672725 0.89 HTR6 (0.74) HTR6
SCHEMBL4676589 0.89 HTR6 (0.74) HTR6
SCHEMBL3339149 0.89 HTR6 (0.70) HTR6
Hydrochloric Acid SCHEMBL4673582 0.89 HTR6 (0.62) HTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080039462-A1 Compounds having 5-HT6 receptor affinity MEMORY PHARMACEUTICALS CORPORATION 2008-02-14 US claimed
EP-1964544-B2 Sensitive skin perfumes TAKASAGO PERFUMERY CO LTD (JP) 2023-08-02 EP disclosed
EP-1964544-B1 Sensitive skin perfumes TAKASAGO PERFUMERY CO LTD (JP) 2017-07-26 EP disclosed
US-20100152306-A1 Sensitive Skin Perfumes TAKASAGO INTERNATIONAL CORPORATION (JP) 2010-06-17 US disclosed
US-20100152177-A1 COMPOUNDS HAVING 5-HT6 RECEPTOR AFFINITY MEMORY PHARMACEUTICALS CORPORATION (US) 2010-06-17 US disclosed
US-20100152177-A1 COMPOUNDS HAVING 5-HT6 RECEPTOR AFFINITY MEMORY PHARMACEUTICALS CORPORATION (US) 2010-06-17 US disclosed
US-20100152177-A1 COMPOUNDS HAVING 5-HT6 RECEPTOR AFFINITY MEMORY PHARMACEUTICALS CORPORATION (US) 2010-06-17 US disclosed
US-7696229-B2 Compounds having 5-HT6 receptor affinity MEMORY PHARMACEUTICALS CORPORATION (US) 2010-04-13 US disclosed
US-7696229-B2 Compounds having 5-HT6 receptor affinity MEMORY PHARMACEUTICALS CORPORATION (US) 2010-04-13 US disclosed
US-7696229-B2 Compounds having 5-HT6 receptor affinity MEMORY PHARMACEUTICALS CORPORATION (US) 2010-04-13 US disclosed
US-20080241201-A1 Cosmetics, toiletries, personal care and cleansing, household cleaning and laundry products having two to ten well characterized fragrances; hypoallergenic TAKASAGO INTERNATIONAL CORPORATION (JP) 2008-10-02 US disclosed
EP-1964544-A1 Sensitive skin perfumes Takasago International Corporation (JP) 2008-09-03 EP disclosed
EP-1964542-A1 Sensitive skin perfumes Takasago International Corporation (JP) 2008-09-03 EP disclosed
US-20080039462-A1 Compounds having 5-HT6 receptor affinity MEMORY PHARMACEUTICALS CORPORATION 2008-02-14 US disclosed
US-20080039462-A1 Compounds having 5-HT6 receptor affinity MEMORY PHARMACEUTICALS CORPORATION 2008-02-14 US disclosed
US-20080039462-A1 Compounds having 5-HT6 receptor affinity MEMORY PHARMACEUTICALS CORPORATION 2008-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100152177-A1 COMPOUNDS HAVING 5-HT6 RECEPTOR AFFINITY HTR6, HTR3B, HTR1B HTR6 1/4885SCN9A 1368/4885
US-20080039462-A1 Compounds having 5-HT6 receptor affinity HTR6, HTR3B, HTR1B HTR6 1/4885SCN9A 1368/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.