Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | GUSB | P08236 | 1/20 | 0.55 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.55 |
| ▸ | CDK1 | P06493 | 2/20 | 0.53 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.53 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.53 |
| ▸ | GSK3A | P49840 | 1/20 | 0.53 |
| ▸ | GSK3B | P49841 | 1/20 | 0.53 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.53 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.53 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.53 |
| ▸ | F7 | P08709 | 1/20 | 0.50 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | CDK2 | P24941 | 1/20 | 0.48 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.48 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 2/20 | 0.45 |
| ▸ | MGAM | O43451 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15633796 | 0.80 | NPC1 (0.46) | KDM4EHPGDCDK1CCNB2CCNB1 | |
| SCHEMBL30802382 | 0.79 | MKNK1 (0.69) | KDM4EHPGDRIPK1CDK1CDK2 | |
| SCHEMBL10740734 | 0.79 | PDE5A (0.65) | PDE5AKDM4EHPGDGUSBRIPK1 | |
| SCHEMBL30874526 | 0.79 | MKNK1 (0.69) | KDM4EHPGDRIPK1CDK1CDK2 | |
| SCHEMBL26227556 | 0.79 | MKNK1 (0.69) | KDM4EHPGDRIPK1CDK1CDK2 | |
| SCHEMBL2191709 | 0.77 | MKNK1 (0.68) | KDM4EHPGDCDK1CDK2MKNK1 | |
| SCHEMBL461968 | 0.76 | F7 (0.79) | PDE5AKDM4EHPGDGUSBCDK1 | |
| SCHEMBL29578227 | 0.76 | F7 (0.79) | PDE5AKDM4EHPGDGUSBCDK1 | |
| SCHEMBL2668125 | 0.76 | NPC1 (0.56) | KDM4EHPGDCDK1CCNB2CCNB1 | |
| SCHEMBL5246817 | 0.75 | KDM4E (0.53) | PDE5AKDM4EHPGDGUSBCDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100151234-A1 | Penetration Resistant Composite and Article Comprising Same | E. I. DU PONT DE NEMOURS AND COMPANY | 2010-06-17 | — | — | US | disclosed |
| CN-101283232-A | Penetration resistant composite and article comprising same | DU PONT (US) | 2008-10-08 | — | — | CN | disclosed |
| EP-1920210-A2 | PENETRATION RESISTANT COMPOSITE AND ARTICLE COMPRISING SAME | E.I.Du pont de nemours and company (US) | 2008-05-14 | — | — | EP | disclosed |
| WO-2007133238-A2 | PENETRATION RESISTANT COMPOSITE AND ARTICLE COMPRISING SAME | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-11-22 | — | — | WO | disclosed |