Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | RPA1 | P27694 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | STAT1 | P42224 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16355305 | 0.88 | KDM4E (0.59) | RAB9ANPC1LMNAKDM4EHPGD | |
| SCHEMBL18593568 | 0.75 | KDM4E (0.73) | RAB9ANPC1LMNAKDM4EHPGD | |
| SCHEMBL31613089 | 0.74 | KDM4E (0.59) | RAB9ANPC1LMNAKDM4EHPGD | |
| SCHEMBL3678246 | 0.74 | KDM4E (0.59) | RAB9ANPC1LMNAKDM4EHPGD | |
| SCHEMBL28096984 | 0.74 | KDM4E (0.58) | RAB9ANPC1LMNAKDM4EHPGD | |
| SCHEMBL7649625 | 0.73 | NPC1 (0.51) | RAB9ANPC1LMNAKDM4EHPGD | |
| SCHEMBL12983431 | 0.72 | GRM2 (0.44) | RAB9ANPC1LMNAKDM4EHPGD | |
| SCHEMBL11565469 | 0.72 | HSD17B10 (0.47) | RAB9ANPC1KDM4EHPGDADORA2A | |
| SCHEMBL9813570 | 0.70 | NPC1 (0.51) | RAB9ANPC1LMNAKDM4EHPGD | |
| SCHEMBL294530 | 0.70 | NPC1 (0.56) | RAB9ANPC1LMNAKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-63022845-A | — | — | None | — | — | JP | disclosed |
| EP-4240579-B1 | METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES | ALCON INC (CH) | 2024-12-04 | — | — | EP | disclosed |
| EP-4121279-B1 | METHOD FOR PRODUCING EMBEDDED OR HYBRID HYDROGEL CONTACT LENSES | ALCON INC (CH) | 2024-07-10 | — | — | EP | disclosed |
| US-10598825-B2 | Soft silicone medical devices with durable lubricious coatings thereon | ALCON INC. (CH) | 2020-03-24 | — | — | US | disclosed |
| US-20190257980-A1 | SOFT SILICONE MEDICAL DEVICES WITH DURABLE LUBRICIOUS COATINGS THEREON | ALCON INC. (CH) | 2019-08-22 | — | — | US | disclosed |
| US-10324233-B2 | Soft silicone medical devices with durable lubricious coatings thereon | NOVARTIS AG (CH) | 2019-06-18 | — | — | US | disclosed |
| US-20170068018-A1 | SOFT SILICONE MEDICAL DEVICES WITH DURABLE LUBRICIOUS COATINGS THEREON | ALCON INC. (CH) | 2017-03-09 | — | — | US | disclosed |
| US-7732077-B2 | Polymer electrolyte medium and direct methanol fuel cell | KABUSHIKI KAISHA TOSHIBA (JP) | 2010-06-08 | — | — | US | disclosed |
| EP-1693917-B1 | Polymer Electrolyte Medium and Direct Methanol Fuel Cell | TOSHIBA KK (JP) | 2007-05-30 | — | — | EP | disclosed |
| EP-1693917-A1 | Polymer Electrolyte Medium and Direct Methanol Fuel Cell | Kabushiki Kaisha Toshiba (JP) | 2006-08-23 | — | — | EP | disclosed |
| US-20060177721-A1 | Polymer electrolyte medium and direct methanol fuel cell | KABUSHIKI KAISHA TOSHIBA | 2006-08-10 | — | — | US | disclosed |
| JP-S6322845-A | HIGH POLYMER MATERIAL COMPOSITION HAVING IMPROVED LIGHT RESISTANCE | MORISAWA SHOJI KK | 1988-01-30 | — | — | JP | disclosed |