SCHEMBL16355305

SCHEMBL16355305

Cc1cccc(-n2nc3ccccc3n2)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.59
HPGD P15428 2/20 0.59
NPC1 O15118 5/20 0.51
RAB9A P51151 5/20 0.51
LMNA P02545 1/20 0.51
ALDH1A1 P00352 5/20 0.47
HTT P42858 1/20 0.47
MEN1 O00255 2/20 0.46
MAPT P10636 2/20 0.46
KMT2A Q03164 2/20 0.46
STAT1 P42224 1/20 0.46
ADORA2A P29274 3/20 0.46
ADORA3 P0DMS8 2/20 0.46
ADORA1 P30542 2/20 0.46
HSP90AA1 P07900 1/20 0.44
MGLL Q99685 1/20 0.44
SMN1; SMN2 Q16637 2/20 0.43
TP53 P04637 1/20 0.43
GAA P10253 1/20 0.43
CASP1 P29466 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3339236 0.88 RAB9A (0.50) KDM4EHPGDNPC1RAB9ALMNA
SCHEMBL18593568 0.85 KDM4E (0.73) KDM4EHPGDNPC1RAB9ALMNA
SCHEMBL28096984 0.83 KDM4E (0.58) KDM4EHPGDNPC1RAB9ALMNA
SCHEMBL7575228 0.79 KDM4E (0.64) KDM4EHPGDNPC1RAB9ALMNA
SCHEMBL14281017 0.79 ADORA3 (0.46) KDM4EHPGDNPC1RAB9ALMNA
SCHEMBL3226780 0.78 KDM4E (0.63) KDM4EHPGDNPC1RAB9ALMNA
SCHEMBL11565469 0.78 HSD17B10 (0.47) KDM4EHPGDNPC1RAB9AALDH1A1
SCHEMBL11542701 0.77 KDM4E (0.67) KDM4EHPGDNPC1RAB9ALMNA
SCHEMBL3228579 0.76 KDM4E (0.59) KDM4EHPGDNPC1RAB9ALMNA
SCHEMBL5543884 0.76 KDM4E (0.59) KDM4EHPGDNPC1RAB9ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117986487-A Modified polyglycolic acid raw material composition with improved compressive property, modified polyglycolic acid, preparation method and application thereof 中国石油化工股份有限公司 2024-05-07 CN claimed
CN-117986487-A Modified polyglycolic acid raw material composition with improved compressive property, modified polyglycolic acid, preparation method and application thereof 中国石油化工股份有限公司 2024-05-07 CN disclosed
CN-108778991-B Ion scavenger for solar cell, solar cell sealing agent composition containing same, and solar cell module 东亚合成株式会社 2021-11-16 CN disclosed
US-9123897-B2 Benzotriazole derivatives and organic electroluminescent devices using the derivatives HODOGAYA CHEMICAL CO., LTD. (JP) 2015-09-01 US disclosed
US-20140374721-A1 NOVEL BENZOTRIAZOLE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT DEVICES USING THE DERIVATIVES HODOGAYA CHEMICAL CO., LTD (JP) 2014-12-25 US disclosed