SCHEMBL3339449

SCHEMBL3339449

Cc1ccc(N=Nc2ccc(N)cc2)cc1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 10/20 0.74
RAB9A P51151 7/20 0.74
NPC1 O15118 7/20 0.74
TDP1 Q9NUW8 7/20 0.74
L3MBTL1 Q9Y468 4/20 0.74
SMN1; SMN2 Q16637 4/20 0.74
MEN1 O00255 3/20 0.74
KMT2A Q03164 3/20 0.74
ACHE P22303 2/20 0.68
PKM P14618 2/20 0.61
HTT P42858 1/20 0.61
MAPK1 P28482 2/20 0.57
ATM Q13315 1/20 0.57
TEAD4 Q15561 1/20 0.52
POLB P06746 2/20 0.50
GAA P10253 2/20 0.50
CA12 O43570 2/20 0.50
CA2 P00918 2/20 0.50
CA9 Q16790 2/20 0.50
ALDH1A1 P00352 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3339447 1.00 MAPT (0.74) MAPTRAB9ANPC1TDP1L3MBTL1
SCHEMBL18806559 1.00 MAPT (0.74) MAPTRAB9ANPC1TDP1L3MBTL1
SCHEMBL11318226 0.86 MAPT (1.00) MAPTRAB9ANPC1TDP1L3MBTL1
SCHEMBL205992 0.86 MAPT (1.00) MAPTRAB9ANPC1TDP1L3MBTL1
SCHEMBL11329248 0.86 MAPT (1.00) MAPTRAB9ANPC1TDP1L3MBTL1
SCHEMBL11329238 0.86 MAPT (1.00) MAPTRAB9ANPC1TDP1L3MBTL1
SCHEMBL11329226 0.86 MAPT (1.00) MAPTRAB9ANPC1TDP1L3MBTL1
SCHEMBL16556 0.86 MAPT (1.00) MAPTRAB9ANPC1TDP1L3MBTL1
SCHEMBL11693056 0.86 NPC1 (0.61) MAPTRAB9ANPC1TDP1L3MBTL1
SCHEMBL1405393 0.86 NPC1 (0.61) MAPTRAB9ANPC1TDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110788766-B Intelligent organic grinding tool and preparation method and recovery method thereof 郑州磨料磨具磨削研究所有限公司 2021-06-18 CN disclosed
CN-110788766-A Intelligent organic grinding tool and preparation method and recovery method thereof 郑州磨料磨具磨削研究所有限公司 2020-02-14 CN disclosed
US-10005960-B2 Composition and polarizing film SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-06-26 US disclosed
US-20170327743-A1 LIQUID CRYSTAL DISPLAY DEVICE AND METHOD FOR MANUFACTURING SAME JNC CORP (JP) 2017-11-16 US disclosed
US-9771519-B2 Liquid crystal display device and method for manufacturing same JNC CORPORATION (JP) 2017-09-26 US disclosed
US-20170240810-A1 DICHROIC DYE COMPOUND, POLARIZING FILM, AND USES THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-08-24 US disclosed
US-20170240810-A1 DICHROIC DYE COMPOUND, POLARIZING FILM, AND USES THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-08-24 US disclosed
US-20170121605-A1 COMPOSITION AND POLARIZING FILM SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-05-04 US disclosed
US-20150275089-A1 LIQUID CRYSTAL DISPLAY ELEMENT AND METHOD FOR MANUFACTURING SAME JNC PETROCHEMICAL CORPORATION (JP) 2015-10-01 US disclosed
US-20100162416-A1 Multi-stage stem cell carcinogenesis STEMLIFELINE, INC. (US) 2010-06-24 US disclosed
WO-2010037134-A2 MULTI-STAGE STEM CELL CARCINOGENESIS STEMLIFELINE, INC. (US) 2010-04-01 WO disclosed
US-5424404-A Colorfastness, discoloration inhibition, red and yellow color; coloring paper, leather, printing on polymeric material BASF AKTIENGESELLSCHAFT (DE) 1995-06-13 US disclosed
EP-0046729-B1 PROCESS FOR THE MASS COLOURING OF POLYAMIDE FIBRES WITH AZO DYESTUFFS CIBA-GEIGY AG (CH) 1984-12-19 EP disclosed
US-4396545-A Bis(arylazo)diimides pigments GULF OIL CORPORATION (US) 1983-08-02 US disclosed
EP-0046729-A2 Process for the mass colouring of polyamide fibres with azo dyestuffs CIBA-GEIGY AG (CH) 1982-03-03 EP disclosed
US-4225493-A FOR POLYAMIDES BAYER AKTIENGESELLSCHAFT (DE) 1980-09-30 US disclosed
US-4056367-A DYEING PETROLEUM, INKS, FATS, WAXES, PLASTICS PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1977-11-01 US disclosed
US-3988312-A TETRAKISAZO DYES CIBA-GEIGY CORPORATION (US) 1976-10-26 US disclosed