Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.74 |
| ▸ | RAB9A | P51151 | 7/20 | 0.74 |
| ▸ | NPC1 | O15118 | 7/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.74 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.74 |
| ▸ | MEN1 | O00255 | 3/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.74 |
| ▸ | ACHE | P22303 | 2/20 | 0.68 |
| ▸ | PKM | P14618 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18806559 | 1.00 | MAPT (0.74) | MAPTRAB9ANPC1TDP1L3MBTL1 | |
| SCHEMBL3339449 | 1.00 | MAPT (0.74) | MAPTRAB9ANPC1TDP1L3MBTL1 | |
| SCHEMBL11318226 | 0.86 | MAPT (1.00) | MAPTRAB9ANPC1TDP1L3MBTL1 | |
| SCHEMBL205992 | 0.86 | MAPT (1.00) | MAPTRAB9ANPC1TDP1L3MBTL1 | |
| SCHEMBL11329248 | 0.86 | MAPT (1.00) | MAPTRAB9ANPC1TDP1L3MBTL1 | |
| SCHEMBL11329238 | 0.86 | MAPT (1.00) | MAPTRAB9ANPC1TDP1L3MBTL1 | |
| SCHEMBL11329226 | 0.86 | MAPT (1.00) | MAPTRAB9ANPC1TDP1L3MBTL1 | |
| SCHEMBL16556 | 0.86 | MAPT (1.00) | MAPTRAB9ANPC1TDP1L3MBTL1 | |
| SCHEMBL11693056 | 0.86 | NPC1 (0.61) | MAPTRAB9ANPC1TDP1L3MBTL1 | |
| SCHEMBL1405393 | 0.86 | NPC1 (0.61) | MAPTRAB9ANPC1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110788766-B | Intelligent organic grinding tool and preparation method and recovery method thereof | 郑州磨料磨具磨削研究所有限公司 | 2021-06-18 | — | — | CN | disclosed |
| CN-110788766-A | Intelligent organic grinding tool and preparation method and recovery method thereof | 郑州磨料磨具磨削研究所有限公司 | 2020-02-14 | — | — | CN | disclosed |
| US-9981038-B2 | Photoswitchable HDAC inhibitors | THE GENERAL HOSPITAL CORPORATION (US) | 2018-05-29 | — | — | US | disclosed |
| US-9688617-B2 | Photoreactive synthetic regulator of protein function and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-06-27 | — | — | US | disclosed |
| US-20160229794-A1 | PHOTOREACTIVE SYNTHETIC REGULATOR OF PROTEIN FUNCTION AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2016-08-11 | — | — | US | disclosed |
| US-9334231-B2 | Photoreactive synthetic regulator of protein function and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-05-10 | — | — | US | disclosed |
| US-20160022817-A1 | Photoswitchable HDAC Inhibitors | THE GENERAL HOSPITAL CORPORATION (US) | 2016-01-28 | — | — | US | disclosed |
| US-9057020-B2 | Black dichroic dye | BASF SE (DE) | 2015-06-16 | — | — | US | disclosed |
| US-20150158811-A1 | PHOTOREACTIVE SYNTHETIC REGULATOR OF PROTEIN FUNCTION AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2015-06-11 | — | — | US | disclosed |
| US-20150119356-A1 | Ophthalmic Viscoelastic Device | CARL ZEISS MEDITEC AG (DE) | 2015-04-30 | — | — | US | disclosed |
| US-7951607-B2 | Compositions and methods for detecting nerve agents | UNIVERSITY OF WYOMING (US) | 2011-05-31 | — | — | US | disclosed |
| US-20100162416-A1 | Multi-stage stem cell carcinogenesis | STEMLIFELINE, INC. (US) | 2010-06-24 | — | — | US | disclosed |
| US-20100130757-A1 | COMPOSITIONS AND METHODS FOR DETECTING NERVE AGENTS | UNIVERSITY OF WYOMING (US) | 2010-05-27 | — | — | US | disclosed |
| WO-2010037134-A2 | MULTI-STAGE STEM CELL CARCINOGENESIS | STEMLIFELINE, INC. (US) | 2010-04-01 | — | — | WO | disclosed |
| US-7674627-B2 | Compositions and methods for detecting nerve agents | UNIVERSITY OF WYOMING (US) | 2010-03-09 | — | — | US | disclosed |
| US-20100022008-A1 | COMPOSITIONS AND METHODS FOR DETECTING NERVE AGENTS | UNIVERSITY OF WYOMING | 2010-01-28 | — | — | US | disclosed |
| US-5424404-A | Colorfastness, discoloration inhibition, red and yellow color; coloring paper, leather, printing on polymeric material | BASF AKTIENGESELLSCHAFT (DE) | 1995-06-13 | — | — | US | disclosed |
| US-4225493-A | FOR POLYAMIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1980-09-30 | — | — | US | disclosed |
| US-4056367-A | DYEING PETROLEUM, INKS, FATS, WAXES, PLASTICS | PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1977-11-01 | — | — | US | disclosed |
| US-3988312-A | TETRAKISAZO DYES | CIBA-GEIGY CORPORATION (US) | 1976-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150158811-A1 | PHOTOREACTIVE SYNTHETIC REGULATOR OF PROTEIN FUNCTION AND METHODS OF USE THEREOF | PPP1R10, PPP6R1, PPP6R3 | MAPT 4166/4885RAB9A 966/4885NPC1 4575/4885 |
| US-20160229794-A1 | PHOTOREACTIVE SYNTHETIC REGULATOR OF PROTEIN FUNCTION AND METHODS OF USE THEREOF | PPP1R10, PPP6R1, PPP6R3 | MAPT 4166/4885RAB9A 966/4885NPC1 4575/4885 |
| US-20150119356-A1 | Ophthalmic Viscoelastic Device | UACA, ICAM1, VIM | MAPT 499/4885RAB9A 3139/4885NPC1 4214/4885 |
| US-20160022817-A1 | Photoswitchable HDAC Inhibitors | HDAC1, HDAC4, HDAC3 | MAPT 465/4885RAB9A 3084/4885NPC1 4062/4885 |
| US-20100130757-A1 | COMPOSITIONS AND METHODS FOR DETECTING NERVE AGENTS | PHOSPHO1, NCS1, GAP43 | MAPT 2630/4885RAB9A 2094/4885NPC1 4618/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.