SCHEMBL3339612

SCHEMBL3339612

O=C(O)c1c(Cl)c(C(=O)O)c(C(=O)O)c(Cl)c1C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.43
HTT P42858 1/20 0.41
CYP1A2 P05177 1/20 0.40
ALDH1A1 P00352 3/20 0.37
KDM4E B2RXH2 1/20 0.37
HSD17B10 Q99714 1/20 0.37
MAPK1 P28482 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
TSHR P16473 4/20 0.36
ALOX15 P16050 1/20 0.36
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36
CA14 Q9ULX7 1/20 0.36
TPMT P51580 1/20 0.36
CYP3A4 P08684 1/20 0.33
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8125151 0.96 DPP4 (0.42) DPP4HTTCYP1A2ALDH1A1KDM4E
SCHEMBL10617916 0.93 HTT (0.43) DPP4HTTCYP1A2ALDH1A1KDM4E
SCHEMBL4159821 0.92 DPP4 (0.43) DPP4HTTCYP1A2ALDH1A1KDM4E
SCHEMBL27772 0.89 HTT (0.50) DPP4HTTCYP1A2ALDH1A1KDM4E
Hydrochloric Acid SCHEMBL29253982 0.89 DPP4 (0.42) DPP4HTTCYP1A2ALDH1A1KDM4E
SCHEMBL29431520 0.89 HTT (0.50) DPP4HTTCYP1A2ALDH1A1KDM4E
Hydrochloric Acid SCHEMBL10715453 0.86 HTT (0.48) DPP4HTTCYP1A2ALDH1A1KDM4E
SCHEMBL6903601 0.86 HTT (0.48) DPP4HTTCYP1A2ALDH1A1KDM4E
SCHEMBL347404 0.86 DPP4 (0.40) DPP4HTTCYP1A2ALDH1A1KDM4E
SCHEMBL5406015 0.86 HTT (0.43) DPP4HTTCYP1A2ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114854711-B Hot start Taq DNA polymerase and preparation method and application thereof 北京丹大生物技术有限公司 2024-02-27 CN claimed
CN-115011579-A Taq DNA polymerase mutant and preparation method and application thereof 北京丹大生物技术有限公司 2022-09-06 CN claimed
CN-114854711-A Hot-start Taq DNA polymerase and preparation method and application thereof 北京丹大生物技术有限公司 2022-08-05 CN claimed
CN-112359031-A Hot-start DNA polymerase and preparation method and application thereof 北京丹大生物技术有限公司 2021-02-12 CN claimed
CN-114854711-B Hot start Taq DNA polymerase and preparation method and application thereof 北京丹大生物技术有限公司 2024-02-27 CN disclosed
CN-114854711-B Hot start Taq DNA polymerase and preparation method and application thereof 北京丹大生物技术有限公司 2024-02-27 CN disclosed
CN-115011579-A Taq DNA polymerase mutant and preparation method and application thereof 北京丹大生物技术有限公司 2022-09-06 CN disclosed
CN-114854711-A Hot-start Taq DNA polymerase and preparation method and application thereof 北京丹大生物技术有限公司 2022-08-05 CN disclosed
CN-114854711-A Hot-start Taq DNA polymerase and preparation method and application thereof 北京丹大生物技术有限公司 2022-08-05 CN disclosed
CN-112359031-A Hot-start DNA polymerase and preparation method and application thereof 北京丹大生物技术有限公司 2021-02-12 CN disclosed
US-10696845-B2 Energy-sensitive resin composition TOKYO OHKA KOGYO CO., LTD. (JP) 2020-06-30 US disclosed
EP-3275940-B1 ENERGY-SENSITIVE RESIN COMPOSITION TOKYO OHKA KOGYO CO LTD (JP) 2019-12-18 EP disclosed
US-6924348-B2 Polyamide acid and polyimide, and optical material NIPPON SHOKUBAI CO., LTD. (JP) 2005-08-02 US disclosed
CN-1623107-A Optical film, laminated polarizing plate, liquid crystal display using the same, and self-light-emitting display using the same NITTO DENKO CORP (JP) 2005-06-01 CN disclosed
CN-1569995-A Method and apparatus for production of fluorine-containing polyimide film NIPPON CATALYTIC CHEM IND (JP) 2005-01-26 CN disclosed
US-20040234686-A1 Method and apparatus for production of fluorine-containing polyimide film NIPPON SHOKUBAI CO., LTD. (JP) 2004-11-25 US disclosed
EP-1454945-A1 Method and apparatus for production of fluorine-containing polyimide film Nippon Shokubai Co., Ltd. (JP) 2004-09-08 EP disclosed
US-20030050407-A1 Polyamide acid and polyimide, and optical material NIPPON SHOKUBAI CO., LTD (JP) 2003-03-13 US disclosed
CN-1397583-A Polyamic acid, polyimide and optical material NIPPON CATALYTIC CHEM IND (JP) 2003-02-19 CN disclosed
EP-1275679-A1 Polyamide acid and polyimide, and optical material Nippon Shokubai Co., Ltd. (JP) 2003-01-15 EP disclosed