SCHEMBL3340936

SCHEMBL3340936

Oc1cc(CSc2cccc(F)c2F)nc2cc(-c3cc(Cl)cc(Cl)c3)nn12

nearest known ligand 0.48

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CXCR2 P25025 18/20 0.48
FYN P06241 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3337864 0.93 CXCR2 (0.49) CXCR2FYN
SCHEMBL3337830 0.90 CXCR2 (0.52) CXCR2FYN
SCHEMBL3339100 0.89 CXCR2 (0.46) CXCR2
SCHEMBL3336538 0.88 CXCR2 (0.49) CXCR2FYN
SCHEMBL3340295 0.87 CXCR2 (0.48) CXCR2FYN
SCHEMBL3341508 0.84 CXCR2 (0.48) CXCR2FYN
SCHEMBL3338731 0.84 CXCR2 (0.46) CXCR2FYN
SCHEMBL3338486 0.83 CXCR2 (0.46) CXCR2FYN
SCHEMBL2638147 0.83 CXCR2 (0.52) CXCR2
SCHEMBL3340771 0.82 CXCR2 (0.43) CXCR2FYN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2950910-A2 CARBON CAPTURE SOLVENTS AND METHODS FOR USING SUCH SOLVENTS Carbon Clean Solutions Pvt. Ltd. (IN) 2015-12-09 EP claimed
WO-2014118633-A2 CARBON CAPTURE SOLVENTS AND METHODS FOR USING SUCH SOLVENTS CARBON CLEAN SOLUTIONS PVT, LTD (IN) 2014-08-07 WO claimed
US-20100152205-A1 CXCR2 INHIBITORS NOVARTIS AG 2010-06-17 US claimed
WO-2018152438-A1 AMINE-APPENDED METAL-ORGANIC FRAMEWORKS EXHIBITING A NEW ADSORPTION MECHANISM FOR CARBON DIOXIDE SEPARATIONS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2018-08-23 WO disclosed
US-20100152205-A1 CXCR2 INHIBITORS NOVARTIS AG 2010-06-17 US disclosed
US-20100152205-A1 CXCR2 INHIBITORS NOVARTIS AG 2010-06-17 US disclosed
US-20100152205-A1 CXCR2 INHIBITORS NOVARTIS AG 2010-06-17 US disclosed
EP-2094697-A1 5-SULFANYLMETHYL-PYRAZOLO [1,5-A]PYRIMIDIN-7-OL DERIVATIVES AS CXCR2 ANTAGONISTS Novartis AG (CH) 2009-09-02 EP disclosed
EP-2094644-A2 PROCESS FOR PREPARING 2-AMINO-5-CYANOBENZOIC ACID DERIVATIVES E. I. Du Pont de Nemours and Company (US) 2009-09-02 EP disclosed
WO-2008082502-A2 PROCESS FOR PREPARING 2-AMINO-5-CYANOBENZOIC ACID DERIVATIVES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2008-07-10 WO disclosed
WO-2008062026-A1 5-SULFANYLMETHYL-PYRAZOLO [1,5-A] PYRIMIDIN-7-OL DERIVATIVES AS CXCR2 ANTAGONISTS NOVARTIS AG (CH) 2008-05-29 WO disclosed
WO-2008062026-A1 5-SULFANYLMETHYL-PYRAZOLO [1,5-A] PYRIMIDIN-7-OL DERIVATIVES AS CXCR2 ANTAGONISTS NOVARTIS AG (CH) 2008-05-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100152205-A1 CXCR2 INHIBITORS CXCR2, CXCR1, CXCR3 CXCR2 1/4885FYN 890/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.