SCHEMBL334116

SCHEMBL334116

FC(F)(F)c1n[c]no1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2178784 0.64
SCHEMBL2045264 0.64
SCHEMBL2176892 0.63
SCHEMBL3965118 0.62 LMNA (0.44)
SCHEMBL2812763 0.61
SCHEMBL2043536 0.56
SCHEMBL1829308 0.55 EPHX2 (0.45)
SCHEMBL18760105 0.54 HDAC4 (0.47)
SCHEMBL15532215 0.53
SCHEMBL15161854 0.53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 281 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117964573-A Dihydrobenzofuran and indene analogs as myocardial segment inhibitors 赛特凯恩蒂克公司 2024-05-03 CN claimed
CN-117924208-A Dihydrobenzofuran and indene analogs as myocardial segment inhibitors 赛特凯恩蒂克公司 2024-04-26 CN claimed
EP-4103555-B1 PREPARATION OF AROMATIC CARBONYL COMPOUNDS BY CATALYTIC OXIDATION WITH MOLECULAR OXYGEN BASF SE (DE) 2024-04-24 EP claimed
WO-2024033458-A1 BICYCLIC TETRAHYDROAZEPINE DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2024-02-15 WO claimed
US-20230278996-A1 YKL-40 INHIBITORS AND THEIR THERAPEUTIC APPLICATIONS MOLECURE S.A. (PL) 2023-09-07 US claimed
US-20230150954-A1 PREPARATION OF AROMATIC CARBONYL COMPOUNDS BY CATALYTIC OXIDATION WITH MOLECULAR OXYGEN BASF SE (DE) 2023-05-18 US claimed
US-20230028964-A1 PREPARATION OF SUBSTITUTED AROMATIC CARBOXAMIDES BASF SE (DE) 2023-01-26 US claimed
EP-4103555-A1 PREPARATION OF AROMATIC CARBONYL COMPOUNDS BY CATALYTIC OXIDATION WITH MOLECULAR OXYGEN BASF SE (DE) 2022-12-21 EP claimed
CN-115087646-A Production of aromatic carbonyl compounds by catalytic oxidation with molecular oxygen 巴斯夫欧洲公司 2022-09-20 CN claimed
CN-114761387-A Preparation of substituted aromatic carboxamides 巴斯夫欧洲公司 2022-07-15 CN claimed
US-5514692-A VIRICIDES STERLING WINTHROP INC. (US) 1996-05-07 US claimed
US-5514679-A TREATMENT OF PICORNAVIRUS INFECTIONS STERLING WINTHROP INC. (US) 1996-05-07 US claimed
WO-1996009822-A1 ANTIPICORNAVIRAL AGENTS SANOFI WINTHROP, INC. (US) 1996-04-04 WO claimed
WO-1995031438-A1 THERAPEUTIC PHENOXYALKYLHETEROCYCLES SANOFI WINTHROP, INC. (US) 1995-11-23 WO claimed
WO-1995031439-A1 THERAPEUTIC PHENOXYALKYLPYRIDAZINES AND INTERMEDIATES THEREFOR SANOFI WINTHROP, INC. (US) 1995-11-23 WO claimed
WO-1995031452-A1 THERAPEUTIC PHENOXYALKYLAZOLES AND PHENOXYALKYLAZINES SANOFI WINTHROP, INC. (US) 1995-11-23 WO claimed
US-5453433-A Viricides; antiseptics to decontaminate polio, rhino and coxsackie viruses STERLING WINTHROP INC. (US) 1995-09-26 US claimed
EP-0197230-B1 Imidazo[1,2-a]pyrimidines and their salts with the acids, process and intermediates for their preparation, use as medicaments and compositions containing them ROUSSEL-UCLAF (FR) 1990-01-31 EP claimed
US-4703049-A ANTIANXIETY AGENTS, SEDATIVES ROUSSEL UCLAF (FR) 1987-10-27 US claimed
EP-0197230-A1 Imidazo[1,2-a]pyrimidines and their salts with the acids, process and intermediates for their preparation, use as medicaments and compositions containing them ROUSSEL-UCLAF (FR) 1986-10-15 EP claimed