⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thiourea SCHEMBL2557219 | 0.78 | — | — | |
| Bicarbonate SCHEMBL8726606 | 0.78 | — | — | |
| Bicarbonate SCHEMBL8142662 | 0.75 | ACHE (0.50) | — | |
| SCHEMBL11325629 | 0.75 | — | — | |
| Thiourea SCHEMBL11417440 | 0.75 | — | — | |
| SCHEMBL4880341 | 0.72 | — | — | |
| Thiourea SCHEMBL850383 | 0.72 | — | — | |
| Thiourea SCHEMBL30536984 | 0.72 | — | — | |
| Thiourea SCHEMBL1008 | 0.72 | — | — | |
| Thiourea SCHEMBL30536978 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 425 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014070774-A1 | METHODS OF GENERATING BETA-LACTAMASE RESISTANT CARBAPENEM COMPOUNDS | SOUTHERN METHODIST UNIVERSITY (US) | 2014-05-08 | — | — | WO | claimed |
| US-20140121192-A1 | METHODS OF GENERATING BETA-LACTAMASE RESISTANT CARBAPENEM COMPOUNDS | SOUTHERN METHODIST UNIVERSITY (US) | 2014-05-01 | — | — | US | claimed |
| EP-2167081-B1 | BACTERICIDAL ANTI-MRSA ACTIVE PHARMACEUTICAL COMPOSITION CONTAINING CARBAPENEMS | PFAENDLER HANS RUDOLF (DE) | 2013-06-26 | — | — | EP | claimed |
| US-8227506-B2 | Benzamidine compound | AJINOMOTO., INC. (JP) | 2012-07-24 | — | — | US | claimed |
| US-20100173887-A1 | BACTERICIDAL ANTI-MRSA ACTIVE PHARMACEUTICAL COMPOSITION CONTAINING CARBAPENEMS | PFAENDLER HANS RUDOLF | 2010-07-08 | — | — | US | claimed |
| US-20100105731-A2 | NOVEL BENZAMIDINE COMPOUND | AJINOMOTO CO., INC. (JP) | 2010-04-29 | — | — | US | claimed |
| US-20100093738-A1 | Fungicidal Compounds and Fungicidal Compositions | BASF SE (DE) | 2010-04-15 | — | — | US | claimed |
| EP-2167081-A1 | BACTERICIDAL ANTI-MRSA ACTIVE PHARMACEUTICAL COMPOSITION CONTAINING CARBAPENEMS | Pfaendler, Hans Rudolf (DE) | 2010-03-31 | — | — | EP | claimed |
| WO-2010012793-A1 | FUNGICIDE AMINOTHIAZOLE DERIVATIVES | BAYER CROPSCIENCE SA (FR) | 2010-02-04 | — | — | WO | claimed |
| US-20090069180-A1 | 2-SUBSTITUTED PYRIMIDINE DERIVATIVES | BASF SE (DE) | 2009-03-12 | — | — | US | claimed |
| EP-0324418-A2 | Method for production of t-butyl- 3-oxobutyrates and their use | Takeda Chemical Industries, Ltd. (JP) | 1989-07-19 | — | — | EP | claimed |
| EP-0301394-A1 | Stable oxapenem-3-carboxylic acids | Pfaendler, Hans Rudolf, Prof. Dr. (DE) | 1989-02-01 | — | — | EP | claimed |
| US-4729944-A | NONDIFFUSIBLE COUPLER, IMPROVED GRANINESS AND SENSITIVITY | FUJI PHOTO FILM CO., LTD. (JP) | 1988-03-08 | — | — | US | claimed |
| WO-1987007602-A2 | N-(5-SUBSTITUTED METHYLENE) PHENYL HERBICIDES | RHONE-POULENC AGROCHIMIE (FR) | 1987-12-17 | — | — | WO | claimed |
| US-4668783-A | Thiazolylacetamido cephalosporin compounds | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1987-05-26 | — | — | US | claimed |
| US-4447602-A | Process to prepare 7-substituted cephalosporins or 6-substituted penicillins | MERCK & CO., INC. (US) | 1984-05-08 | — | — | US | claimed |
| US-4296236-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1981-10-20 | — | — | US | claimed |
| EP-0000640-B1 | TETRAHYDRO-S-TRIAZINE THIONES, PROCESS FOR THEIR PREPARATION AND ACARICIDAL COMPOSITIONS CONTAINING THEM. | Pfizer Limited (GB) | 1981-06-03 | — | — | EP | claimed |
| EP-0000640-A1 | Tetrahydro-s-triazine thiones, process for their preparation and acaricidal compositions containing them. | Pfizer Limited (GB) | 1979-02-07 | — | — | EP | claimed |
| US-4041029-A | Acylimine cephalosporins | MERCK & CO., INC. (US) | 1977-08-09 | — | — | US | claimed |