Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 4/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.37 |
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | PRKACA | P17612 | 1/20 | 0.35 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.35 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.35 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.35 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.35 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.35 |
| ▸ | Q6ZSR9 | Q6ZSR9 | 1/20 | 0.35 |
| ▸ | BMP2K | Q9NSY1 | 1/20 | 0.35 |
| ▸ | CDC42BPB | Q9Y5S2 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | FPR2 | P25090 | 1/20 | 0.34 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3342675 | 0.81 | GPR119 (0.52) | GPR119CYP2C9KCNH2 | |
| SCHEMBL3344880 | 0.80 | GPR119 (0.50) | GPR119 | |
| SCHEMBL3344194 | 0.73 | KCNH2 (0.45) | ROCK1GPR119IKBKBROCK2PRKACA | |
| SCHEMBL12262486 | 0.69 | MLNR (0.47) | PARP1FPR2PROKR1 | |
| SCHEMBL12333861 | 0.69 | GPR119 (0.45) | ROCK1GPR119IKBKBROCK2PRKACA | |
| SCHEMBL2556461 | 0.68 | GPR119 (0.61) | GPR119CYP2C9 | |
| SCHEMBL14634843 | 0.68 | GPR119 (0.61) | GPR119CYP2C9 | |
| SCHEMBL3346737 | 0.67 | GPR119 (0.49) | GPR119CYP2C9 | |
| SCHEMBL3343172 | 0.67 | GPR119 (0.55) | GPR119CYP2C9 | |
| SCHEMBL5140547 | 0.67 | GPR119 (0.69) | GPR119CYP2C9KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010048149-A2 | HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2010-04-29 | — | — | WO | disclosed |