SCHEMBL3342812

SCHEMBL3342812

CCc1cnc(N2CCC(Oc3ccc(-c4ccc(S(C)(=O)=O)cc4F)cc3)C2)nc1

nearest known ligand 0.59

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 20/20 0.59
KCNH2 Q12809 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3342636 0.95 GPR119 (0.60) GPR119KCNH2
SCHEMBL3343980 0.93 GPR119 (0.51) GPR119
SCHEMBL13423111 0.79 GPR119 (0.57) GPR119KCNH2
SCHEMBL3342654 0.79 GPR119 (0.61) GPR119
SCHEMBL904109 0.77 GPR119 (0.45) GPR119KCNH2
SCHEMBL3343321 0.77 GPR119 (0.55) GPR119KCNH2
SCHEMBL19434293 0.77 GPR119 (0.56) GPR119KCNH2
SCHEMBL14696394 0.77 GPR119 (0.64) GPR119KCNH2
SCHEMBL2551042 0.76 GPR119 (0.59) GPR119KCNH2
SCHEMBL12283007 0.76 GPR119 (0.59) GPR119KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010048149-A2 HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE KALYPSYS, INC. (US) 2010-04-29 WO disclosed