Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.45 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.42 |
| ▸ | CDK9 | P50750 | 2/20 | 0.42 |
| ▸ | HRH1 | P35367 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | SLC9A3 | P48764 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3344012 | 0.83 | GPR119 (0.53) | GPR119EPHX2 | |
| SCHEMBL3341043 | 0.80 | GPR119 (0.62) | GPR119 | |
| SCHEMBL13423111 | 0.79 | GPR119 (0.57) | GPR119 | |
| SCHEMBL3342683 | 0.78 | APP (0.46) | GPR119HRH1PTGS2SLC9A3 | |
| Hydrochloric Acid SCHEMBL3347558 | 0.77 | APP (0.45) | GPR119HRH1PTGS2SLC9A3 | |
| SCHEMBL4717235 | 0.76 | HRH1 (0.56) | GPR119HRH1SMN1; SMN2PTGS2SLC9A3 | |
| Hydrochloric Acid SCHEMBL4105228 | 0.75 | HRH1 (0.54) | GPR119HRH1SMN1; SMN2PTGS2SLC9A3 | |
| SCHEMBL27659933 | 0.75 | GPR119 (0.54) | GPR119PTGS2 | |
| SCHEMBL2555749 | 0.72 | GPR119 (0.56) | GPR119HRH1SMN1; SMN2PTGS2SLC9A3 | |
| SCHEMBL2555752 | 0.72 | GPR119 (0.56) | GPR119HRH1SMN1; SMN2PTGS2SLC9A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010048149-A2 | HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2010-04-29 | — | — | WO | disclosed |