SCHEMBL3343217

SCHEMBL3343217

CC(C)(C)OC(=O)N1CCC(Oc2ccc(-c3cccc(S(C)(=O)=O)c3)cc2)CC1

nearest known ligand 0.69

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 18/20 0.69
CHEK2 O96017 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3343336 0.93 GPR119 (0.64) GPR119
SCHEMBL3341614 0.90 GPR119 (0.69) GPR119
SCHEMBL13324476 0.86 GPR119 (0.91) GPR119
SCHEMBL22174159 0.83 HRH1 (0.48) GPR119
SCHEMBL3343300 0.83 GPR119 (0.69) GPR119
SCHEMBL24721341 0.82 GPR119 (0.53) GPR119CHEK2
SCHEMBL2555906 0.82 GPR119 (1.00) GPR119
SCHEMBL2555904 0.82 GPR119 (1.00) GPR119
SCHEMBL12283335 0.82 GPR119 (1.00) GPR119
SCHEMBL4717931 0.80 GPR119 (0.80) GPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010048149-A2 HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE KALYPSYS, INC. (US) 2010-04-29 WO disclosed