Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 19/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3343621 | 0.90 | GPR119 (0.59) | GPR119CYP3A4CYP2C9 | |
| SCHEMBL3343342 | 0.89 | GPR119 (0.59) | GPR119CYP3A4CYP2C9 | |
| SCHEMBL3341578 | 0.88 | GPR119 (0.63) | GPR119CYP3A4CYP2C9 | |
| SCHEMBL3343623 | 0.86 | GPR119 (0.59) | GPR119CYP3A4CYP2C9 | |
| SCHEMBL3343341 | 0.85 | GPR119 (0.59) | GPR119CYP3A4CYP2C9 | |
| SCHEMBL3346759 | 0.85 | GPR119 (0.62) | GPR119CYP3A4CYP2C9 | |
| SCHEMBL3341829 | 0.85 | GPR119 (0.59) | GPR119CYP3A4CYP2C9 | |
| SCHEMBL3346504 | 0.83 | GPR119 (0.44) | GPR119 | |
| SCHEMBL3343378 | 0.83 | GPR119 (0.57) | GPR119CYP2C9 | |
| SCHEMBL3342693 | 0.82 | GPR119 (0.58) | GPR119CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010048149-A2 | HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2010-04-29 | — | — | WO | disclosed |