Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLG | P54098 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28078340 | 0.72 | POLG (0.36) | POLG | |
| SCHEMBL28417379 | 0.59 | ENPP1 (0.34) | POLG | |
| SCHEMBL4879298 | 0.59 | HPRT1 (0.30) | — | |
| SCHEMBL28199622 | 0.59 | FDPS (0.41) | POLG | |
| Triphosphate SCHEMBL4801863 | 0.59 | FDPS (0.41) | POLG | |
| SCHEMBL686905 | 0.59 | FDPS (0.41) | POLG | |
| SCHEMBL670322 | 0.59 | FDPS (0.41) | POLG | |
| Triphosphate SCHEMBL669449 | 0.57 | FDPS (0.43) | POLG | |
| Triphosphate SCHEMBL29575840 | 0.57 | FDPS (0.43) | POLG | |
| Triphosphate SCHEMBL752824 | 0.57 | FDPS (0.43) | POLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117417872-A | Cell or strain for treating phenylketonuria, medicament and application | 苏州普瑞森生物科技有限公司 | 2024-01-19 | — | — | CN | disclosed |
| EP-2201107-B1 | NOVEL GTP CYCLOHYDROLASE TYPE IB | UNIV WESTERN HEALTH SCIENCES (US) | 2019-01-16 | — | — | EP | disclosed |
| US-20130218546-A1 | NOVEL GTP CYCLOHYDROLASE TYPE IB | WESTERN UNIVERSITY OF HEALTH SCIENCES (US) | 2013-08-22 | — | — | US | disclosed |
| US-8328934-B2 | Crystal of GTP Cyclohydrolase Type IB | WESTERN UNIVERSITY OF HEALTH SCIENCES (US) | 2012-12-11 | — | — | US | disclosed |
| US-20100291608-A1 | NOVEL GTP CYCLOHYDROLASE TYPE IB | WESTERN UNIVERSITY OF HEALTH SCIENCES (US) | 2010-11-18 | — | — | US | disclosed |
| EP-2201107-A2 | NOVEL GTP CYCLOHYDROLASE TYPE IB | Western University Of Health Sciences (US) | 2010-06-30 | — | — | EP | disclosed |
| WO-2010039115-A9 | NOVEL GTP CYCLOHYDROLASE TYPE IB | WESTERN UNIVERSITY OF HEALTH SCIENCES (US) | 2010-05-27 | — | — | WO | disclosed |
| WO-2010039115-A2 | NOVEL GTP CYCLOHYDROLASE TYPE IB | WESTERN UNIVERSITY OF HEALTH SCIENCES (US) | 2010-04-08 | — | — | WO | disclosed |