Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 17/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | STS | P08842 | 1/20 | 0.53 |
| ▸ | NAMPT | P43490 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4519083 | 0.94 | GPR119 (0.76) | GPR119NAMPT | |
| SCHEMBL31616130 | 0.85 | NAMPT (0.61) | GPR119STSNAMPT | |
| SCHEMBL4183357 | 0.84 | GPR119 (0.57) | GPR119STSNAMPT | |
| SCHEMBL4510819 | 0.84 | GPR119 (0.71) | GPR119 | |
| SCHEMBL31615814 | 0.82 | P2RY14 (0.59) | GPR119STSNAMPT | |
| SCHEMBL13324476 | 0.82 | GPR119 (0.91) | GPR119 | |
| SCHEMBL1577926 | 0.82 | GPR119 (0.65) | GPR119 | |
| SCHEMBL12965144 | 0.81 | GPR119 (1.00) | GPR119 | |
| SCHEMBL12965009 | 0.81 | GPR119 (1.00) | GPR119 | |
| SCHEMBL12813380 | 0.81 | GPR119 (1.00) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010048149-A2 | HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2010-04-29 | — | — | WO | disclosed |