⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27610245 | 0.97 | CA12 (0.69) | — | |
| SCHEMBL14782398 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL6483185 | 0.92 | CA12 (0.61) | — | |
| SCHEMBL188638 | 0.89 | CA12 (0.58) | — | |
| Trientine SCHEMBL13685489 | 0.81 | CA12 (0.85) | — | |
| SCHEMBL8886773 | 0.81 | — | — | |
| SCHEMBL25342922 | 0.80 | CA12 (1.00) | — | |
| SCHEMBL15797 | 0.80 | CA12 (1.00) | — | |
| SCHEMBL581603 | 0.80 | CA12 (1.00) | — | |
| SCHEMBL25342018 | 0.80 | CA12 (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1813609-B1 | NOVEL AMINOPYRIDINE DERIVATIVES HAVING SELECTIVE AURORA-A INHIBITORY EFFECT | MSD KK (JP) | 2013-06-19 | — | — | EP | disclosed |
| WO-2010111056-A1 | NOVEL AMINOPYRIDINE DERIVATIVES HAVING AURORA A SELECTIVE INHIBITORY ACTION | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2010-09-30 | — | — | WO | disclosed |
| WO-2010067888-A1 | DIHYDROPYRIMIDOPYRIMIDINE DERIVATIVES | BANYU PHARMACEUTICAL CO.,LTD. (JP) | 2010-06-17 | — | — | WO | disclosed |
| EP-1828165-A1 | NOVEL AMINOPYRIDINE DERIVATIVES HAVING AURORA A SELECTIVE INHIBITORY ACTION | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-09-05 | — | — | EP | disclosed |
| WO-2006046735-A1 | NOVEL AMINOPYRIDINE DERIVATIVES HAVING AURORA A SELECTIVE INHIBITORY ACTION | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2006-05-04 | — | — | WO | disclosed |
| EP-1261356-A2 | FARNESYL PROTEIN TRANSFERASE INHIBITOR COMBINATIONS WITH PLATINUM COMPOUNDS | JANSSEN PHARMACEUTICA N.V. (BE) | 2002-12-04 | — | — | EP | disclosed |
| EP-1261374-A2 | FARNESYL PROTEIN TRANSFERASE INHIBITOR COMBINATIONS WITH FURTHER ANTI-CANCER AGENTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2002-12-04 | — | — | EP | disclosed |
| WO-2001064252-A2 | FARNESYL PROTEIN TRANSFERASE INHIBITOR COMBINATIONS WITH FURTHER ANTI-CANCER AGENTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2001-09-07 | — | — | WO | disclosed |
| WO-2001064226-A2 | FARNESYL PROTEIN TRANSFERASE INHIBITOR COMBINATIONS WITH PLATINUM COMPOUNDS | JANSSEN PHARMACEUTICA N.V. (BE) | 2001-09-07 | — | — | WO | disclosed |