Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.61 |
| ▸ | CA6 | P23280 | 5/20 | 0.61 |
| ▸ | CA7 | P43166 | 5/20 | 0.61 |
| ▸ | CA9 | Q16790 | 5/20 | 0.61 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.61 |
| ▸ | CA5B | Q9Y2D0 | 5/20 | 0.61 |
| ▸ | CA2 | P00918 | 4/20 | 0.61 |
| ▸ | CA4 | P22748 | 4/20 | 0.61 |
| ▸ | CA5A | P35218 | 4/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | CA3 | P07451 | 3/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | CA1 | P00915 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | RECQL | P46063 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14782398 | 0.94 | — | — | |
| SCHEMBL27610245 | 0.94 | CA12 (0.69) | CA12CA6CA7CA9CA14 | |
| SCHEMBL3343779 | 0.92 | — | — | |
| SCHEMBL188638 | 0.86 | CA12 (0.58) | CA12CA6CA7CA9CA14 | |
| Hydrochloric Acid SCHEMBL3221874 | 0.82 | CA12 (0.83) | CA12CA6CA7CA9CA14 | |
| Trientine SCHEMBL13685489 | 0.78 | CA12 (0.85) | CA12CA6CA7CA9CA14 | |
| Hydrochloric Acid SCHEMBL724495 | 0.78 | CA12 (0.85) | CA12CA6CA7CA9CA14 | |
| Trientine SCHEMBL1651076 | 0.78 | CA12 (0.85) | CA12CA6CA7CA9CA14 | |
| Hydrochloric Acid SCHEMBL18760070 | 0.78 | CA12 (0.85) | CA12CA6CA7CA9CA14 | |
| Trientine SCHEMBL8867083 | 0.78 | CA12 (0.85) | CA12CA6CA7CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6973894-B1 | for visually determining the passage of a preselected period of time which is applicable to a wide variety of consumer products, especially for products which have an extended shelf or use life | CHURCH & DWIGHT CO., INC. (US) | 2005-12-13 | — | — | US | disclosed |
| US-20040013048-A1 | Timing device | CHURCH & DWIGHT CO., INC. | 2004-01-22 | — | — | US | disclosed |
| WO-2002039196-A1 | TIMING DEVICE | CHURCH & DWIGHT CO., INC. (US) | 2002-05-16 | — | — | WO | disclosed |
| US-6269764-B1 | Timing device | CHURCH & DWIGHT CO., INC. | 2001-08-07 | — | — | US | disclosed |