Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | PTGDR2 | Q9Y5Y4 | 13/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | IL1B | P01584 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3331488 | 0.83 | KDM4E (0.51) | KDM4EPTGDR2SMN1; SMN2LMNAMEN1 | |
| SCHEMBL3297610 | 0.82 | KDM4E (0.54) | KDM4EPTGDR2SMN1; SMN2LMNAMEN1 | |
| SCHEMBL3303954 | 0.81 | KDM4E (0.53) | KDM4EPTGDR2SMN1; SMN2LMNAMEN1 | |
| SCHEMBL20021122 | 0.80 | KDM4E (0.52) | KDM4EPTGDR2SMN1; SMN2LMNAMEN1 | |
| SCHEMBL3323941 | 0.79 | KDM4E (0.51) | KDM4EPTGDR2SMN1; SMN2LMNAMEN1 | |
| SCHEMBL3324004 | 0.79 | KDM4E (0.48) | KDM4EPTGDR2SMN1; SMN2LMNA | |
| SCHEMBL245240 | 0.78 | NR4A2 (0.45) | KDM4ESMN1; SMN2IL1BLMNAMEN1 | |
| SCHEMBL3314187 | 0.78 | KDM4E (0.50) | KDM4EPTGDR2SMN1; SMN2LMNAMEN1 | |
| SCHEMBL20020731 | 0.77 | KDM4E (0.49) | KDM4EPTGDR2SMN1; SMN2LMNA | |
| SCHEMBL20021165 | 0.77 | KDM4E (0.52) | KDM4EPTGDR2SMN1; SMN2LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012003498-A1 | 2 -QUINOLINYL- ACETIC ACID DERIVATIVES AS HIV ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2012-01-05 | — | — | WO | disclosed |