SCHEMBL3344355

SCHEMBL3344355

CCCCC[C@H](O)/C=C/[C@H]1OC(O)C[C@H](O)[C@@H]1C/C=C\CC(=O)O

nearest known ligand 0.81

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.81
KMT2A Q03164 1/20 0.81
PTGFR P43088 7/20 0.59
ALDH1A1 P00352 6/20 0.58
LMNA P02545 3/20 0.58
TBXA2R P21731 3/20 0.58
SLCO2A1 Q92959 2/20 0.58
PTGER1 P34995 1/20 0.58
PTGER4 P35408 1/20 0.58
PTGER3 P43115 1/20 0.58
PTGDR Q13258 1/20 0.58
HPGD P15428 2/20 0.51
ABCC4 O15439 1/20 0.51
KDM4E B2RXH2 1/20 0.50
HKDC1 Q2TB90 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
SAE1 Q9UBE0 1/20 0.50
UBA2 Q9UBT2 1/20 0.50
PTGDR2 Q9Y5Y4 1/20 0.50
TSHR P16473 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL38663703 1.00 MEN1 (0.81) MEN1KMT2APTGFRALDH1A1LMNA
SCHEMBL29559217 1.00 MEN1 (0.81) MEN1KMT2APTGFRALDH1A1LMNA
SCHEMBL13179231 1.00 MEN1 (0.81) MEN1KMT2APTGFRALDH1A1LMNA
Thromboxane B2 SCHEMBL15263306 0.90 MEN1 (1.00) MEN1KMT2APTGFRALDH1A1LMNA
Thromboxane B2 SCHEMBL13179230 0.90 MEN1 (1.00) MEN1KMT2APTGFRALDH1A1LMNA
Thromboxane B2 SCHEMBL38223 0.90 MEN1 (1.00) MEN1KMT2APTGFRALDH1A1LMNA
Thromboxane B2 SCHEMBL21820779 0.90 MEN1 (1.00) MEN1KMT2APTGFRALDH1A1LMNA
Thromboxane B2 SCHEMBL22972728 0.90 MEN1 (1.00) MEN1KMT2APTGFRALDH1A1LMNA
Thromboxane B2 SCHEMBL23646053 0.87 MEN1 (0.77) MEN1KMT2APTGFRALDH1A1LMNA
SCHEMBL31254102 0.87 MEN1 (0.84) MEN1KMT2APTGFRALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026106210-A1 METABOLITE BIOMARKER FOR PREDICTING THERAPEUTIC RESPONSE OF BIOLOGICAL AGENTS IN ASTHMA 재단법인 아산사회복지재단 2026-05-21 WO disclosed
WO-2024242465-A1 LIPID METABOLITE BIOMARKER FOR PREDICTING ASTHMA TREATMENT RESPONSE TO BIOLOGICAL AGENT AND USE THEREOF 재단법인 아산사회복지재단 2024-11-28 WO disclosed
CN-115656400-B Be used for detecting 11-dehydrothromboxane B in urine 2 Liquid chromatography-tandem mass spectrometry method and kit 大连博源医学科技有限公司 2023-08-18 CN disclosed
US-20230129262-A1 METHODS AND PHARMACEUTICAL COMPOSITIONS OF THROMBOXANE A2 RECEPTOR ANTAGONIST FOR THE TREATMENT OF COVID-19 OGLETREE MARTIN (US) 2023-04-27 US disclosed
EP-4125882-A1 METHODS AND PHARMACEUTICAL COMPOSITIONS OF THROMBOXANE A2 RECEPTOR ANTAGONIST FOR THE TREATMENT OF COVID-19 Ogletree, Martin (US) 2023-02-08 EP disclosed
CN-115656400-A Method for detecting 11-dehydrothromboxane B in urine 2 Liquid chromatography-tandem mass spectrometry method and kit 大连博源医学科技有限公司 2023-01-31 CN disclosed
EP-4119131-A1 DRY POWDER FORMULATIONS FOR INHALATION Otitopic Inc. (US) 2023-01-18 EP disclosed
EP-3107548-B1 DRY POWDER FORMULATIONS FOR INHALATION OTITOPIC INC (US) 2022-06-08 EP disclosed
CN-114404425-A Inhibitor of phosphodiesterase and application thereof 南京中医药大学 2022-04-29 CN disclosed
EP-3638807-B1 MIRNA-574-5P AS A BIOMARKER FOR STRATIFICATION OF PROSTAGLANDIN E-DEPENDENT TUMORS FRAUNHOFER GES FORSCHUNG (DE) 2022-03-30 EP disclosed
EP-0578780-B1 SUPPRESSION OF THROMBOXANE LEVELS BY PERCUTANEOUS ADMINISTRATION OF ASPIRIN KEIMOWITZ RUDOLPH M D (US) 2003-07-02 EP disclosed
EP-0627918-B1 NEW USE OF OMEGA-3-FATTY ACIDS FRESENIUS KABI AB (SE) 2001-10-31 EP disclosed
EP-0377439-B1 Controlled-release, low-dose aspirin STERLING WINTHROP INC (US) 1995-09-13 EP disclosed
EP-0336647-B1 Determination of arachidonic acid derivatives and kits therefore SANKYO CO (JP) 1994-07-13 EP disclosed
EP-0578780-A1 SUPPRESSION OF THROMBOXANE LEVELS BY PERCUTANEOUS ADMINISTRATION OF ASPIRIN GUNDERSON MEDICAL FOUNDATION, LTD. (US) 1994-01-19 EP disclosed
WO-1992020343-A1 SUPPRESSION OF THROMBOXANE LEVELS BY PERCUTANEOUS ADMINISTRATION OF ASPIRIN GUNDERSON MEDICAL FOUNDATION, LTD. (US) 1992-11-26 WO disclosed
EP-0166583-B1 COMPOSITIONS FOR ENZYME IMMUNOASSAY OF PROSTAGLANDINS ONO PHARMACEUTICAL CO., LTD. (JP) 1991-09-18 EP disclosed
EP-0377439-A2 Controlled-release, low-dose aspirin STERLING WINTHROP INC. (US) 1990-07-11 EP disclosed
EP-0336647-A2 Determination of arachidonic acid derivatives and kits therefore Sankyo Company Limited (JP) 1989-10-11 EP disclosed
EP-0166583-A2 Compositions for enzyme immunoassay of prostaglandins ONO PHARMACEUTICAL CO., LTD. (JP) 1986-01-02 EP disclosed