Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 1/20 | 1.00 |
| ▸ | PTGFR | P43088 | 4/20 | 0.74 |
| ▸ | TBXA2R | P21731 | 6/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.73 |
| ▸ | LMNA | P02545 | 4/20 | 0.73 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.73 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.73 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.73 |
| ▸ | SLCO2A1 | Q92959 | 2/20 | 0.73 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.73 |
| ▸ | HPGD | P15428 | 3/20 | 0.64 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.64 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.60 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.58 |
| ▸ | PTGIR | P43119 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thromboxane B2 SCHEMBL15263306 | 1.00 | MEN1 (1.00) | MEN1KMT2APTGFRTBXA2RALDH1A1 | |
| Thromboxane B2 SCHEMBL21820779 | 1.00 | MEN1 (1.00) | MEN1KMT2APTGFRTBXA2RALDH1A1 | |
| Thromboxane B2 SCHEMBL13179230 | 1.00 | MEN1 (1.00) | MEN1KMT2APTGFRTBXA2RALDH1A1 | |
| Thromboxane B2 SCHEMBL38223 | 1.00 | MEN1 (1.00) | MEN1KMT2APTGFRTBXA2RALDH1A1 | |
| SCHEMBL31254102 | 0.92 | MEN1 (0.84) | MEN1KMT2APTGFRTBXA2RALDH1A1 | |
| SCHEMBL29559217 | 0.90 | MEN1 (0.81) | MEN1KMT2APTGFRTBXA2RALDH1A1 | |
| SCHEMBL3344355 | 0.90 | MEN1 (0.81) | MEN1KMT2APTGFRTBXA2RALDH1A1 | |
| SCHEMBL13179231 | 0.90 | MEN1 (0.81) | MEN1KMT2APTGFRTBXA2RALDH1A1 | |
| SCHEMBL38663703 | 0.90 | MEN1 (0.81) | MEN1KMT2APTGFRTBXA2RALDH1A1 | |
| Thromboxane B2 SCHEMBL9545161 | 0.89 | MEN1 (0.79) | MEN1KMT2APTGFRTBXA2RALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210038510-A1 | FORMULATIONS OF KINASE INHIBITORS AND PROSTANOIDS | PULMOKINE, INC. | 2021-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210038510-A1 | FORMULATIONS OF KINASE INHIBITORS AND PROSTANOIDS | PTGIR, PTGIS, PTGFR | MEN1 3677/4885KMT2A 1920/4885PTGFR 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.