Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 13/20 | 0.70 |
| ▸ | MEN1 | O00255 | 5/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.64 |
| ▸ | POLB | P06746 | 4/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.61 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.59 |
| ▸ | NSD2 | O96028 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MPI | P34949 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30862543 | 0.93 | CFTR (0.64) | CFTRMEN1KMT2APOLBNPC1 | |
| SCHEMBL2215803 | 0.84 | CFTR (0.70) | CFTRMEN1KMT2APOLBNLRP3 | |
| SCHEMBL2215801 | 0.84 | CFTR (0.70) | CFTRMEN1KMT2APOLBNLRP3 | |
| SCHEMBL29665058 | 0.84 | CFTR (0.70) | CFTRMEN1KMT2APOLBNLRP3 | |
| SCHEMBL5119828 | 0.84 | CFTR (0.70) | CFTRMEN1KMT2APOLBNLRP3 | |
| SCHEMBL1885719 | 0.82 | CFTR (1.00) | CFTRMEN1KMT2ANLRP3 | |
| SCHEMBL1885717 | 0.82 | CFTR (1.00) | CFTRMEN1KMT2ANLRP3 | |
| SCHEMBL1885715 | 0.82 | CFTR (1.00) | CFTRMEN1KMT2ANLRP3 | |
| SCHEMBL21634346 | 0.82 | CFTR (0.55) | CFTRMEN1KMT2ANLRP3 | |
| SCHEMBL15827152 | 0.82 | CFTR (0.55) | CFTRMEN1KMT2ANLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010044103-A1 | PHARMACEUTICAL COMPOSITION FOR THERAPEUTIC OR PROPHYLACTIC TREATMENT OF BACTERIAL INFECTIONS AND ASSOCIATED DISEASES | NATIONAL INSTITUTE OF IMMUNOLOGY (IN) | 2010-04-22 | — | — | WO | disclosed |