Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SNCA | P37840 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6835952 | 0.83 | POLB (0.52) | MAPTMEN1POLBKMT2AMCL1 | |
| SCHEMBL19511923 | 0.79 | MAPT (0.62) | MAPTMEN1POLBKMT2AMCL1 | |
| SCHEMBL596168 | 0.79 | MAPT (0.62) | MAPTMEN1POLBKMT2AMCL1 | |
| SCHEMBL5952479 | 0.79 | POLB (0.52) | MAPTMEN1POLBKMT2AMCL1 | |
| SCHEMBL11057069 | 0.78 | MAPT (0.50) | MAPTMEN1POLBKMT2AMCL1 | |
| SCHEMBL13183890 | 0.78 | MAPT (0.50) | MAPTMEN1POLBKMT2AMCL1 | |
| SCHEMBL6870230 | 0.78 | TDP1 (0.42) | MAPTMEN1POLBKMT2ATDP1 | |
| SCHEMBL15158311 | 0.78 | TSHR (0.42) | MAPTMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL6834085 | 0.78 | MAPT (0.50) | MAPTMEN1POLBKMT2AMCL1 | |
| SCHEMBL3243151 | 0.77 | MAPT (0.60) | MAPTMEN1POLBKMT2AMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8431747-B2 | Process for the preparation of monomers for polybenzimidazole materials | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-04-30 | — | — | US | disclosed |
| US-8188317-B2 | Integrated process for the preparation of polybenzimidazole precursors | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-05-29 | — | — | US | disclosed |
| US-20100160686-A1 | Process for the Preparation of Monomers for Polybenzimidazole Materials | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-06-24 | — | — | US | disclosed |
| US-20100160675-A1 | INTEGRATED PROCESS FOR THE PREPARATION OF POLYBENZIMIDAZOLE PRECURSORS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100160675-A1 | INTEGRATED PROCESS FOR THE PREPARATION OF POLYBENZIMIDAZOLE PRECURSORS | PUF60, TFPI, CUTA | MAPT 1858/4885MEN1 3134/4885POLB 103/4885 |
| US-20100160686-A1 | Process for the Preparation of Monomers for Polybenzimidazole Materials | PBRM1, PUF60, PARG | MAPT 518/4885MEN1 3012/4885POLB 30/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.