Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TNF | P01375 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | CCR6 | P51684 | 1/20 | 0.44 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.44 |
| ▸ | CBFB | Q13951 | 1/20 | 0.44 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23686780 | 0.87 | KMT2A (0.49) | MAPTL3MBTL1NPC1RAB9APOLB | |
| SCHEMBL3232085 | 0.85 | MAPT (0.50) | MAPTL3MBTL1NPC1RAB9AEPHX2 | |
| SCHEMBL622072 | 0.84 | MAPT (0.49) | MAPTL3MBTL1NPC1RAB9AEPHX2 | |
| SCHEMBL5330174 | 0.83 | TSHR (0.50) | MAPTL3MBTL1NPC1POLBALDH1A1 | |
| SCHEMBL622989 | 0.83 | MAPT (0.48) | MAPTL3MBTL1NPC1RAB9AEPHX2 | |
| SCHEMBL703931 | 0.78 | MAPT (0.72) | MAPTL3MBTL1NPC1RAB9APOLB | |
| SCHEMBL7823277 | 0.77 | NPC1 (0.50) | MAPTL3MBTL1NPC1RAB9APOLB | |
| SCHEMBL2551616 | 0.77 | EPHX2 (0.52) | MAPTEPHX2ALDH1A1LMNATDP1 | |
| SCHEMBL2672619 | 0.75 | MMP8 (0.54) | MAPTNPC1RAB9AEPHX2ALDH1A1 | |
| SCHEMBL5808567 | 0.75 | MAPT (0.52) | MAPTL3MBTL1NPC1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010040989-A1 | QUINOLIN-2-ONE COMPOUNDS | ARGENTA ORAL THERAPEUTICS LIMITED (GB) | 2010-04-15 | — | — | WO | disclosed |