Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.39 |
| ▸ | LPAR2 | Q9HBW0 | 5/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16594794 | 1.00 | THRB (0.40) | THRBMEN1HTTKMT2AMAPT | |
| SCHEMBL10877344 | 1.00 | THRB (0.40) | THRBMEN1HTTKMT2AMAPT | |
| SCHEMBL2632390 | 1.00 | THRB (0.40) | THRBMEN1HTTKMT2AMAPT | |
| SCHEMBL16594587 | 1.00 | THRB (0.40) | THRBMEN1HTTKMT2AMAPT | |
| SCHEMBL1491305 | 1.00 | THRB (0.40) | THRBMEN1HTTKMT2AMAPT | |
| SCHEMBL2121705 | 1.00 | THRB (0.40) | THRBMEN1HTTKMT2AMAPT | |
| SCHEMBL16594894 | 1.00 | THRB (0.40) | THRBMEN1HTTKMT2AMAPT | |
| SCHEMBL15573458 | 1.00 | THRB (0.40) | THRBMEN1HTTKMT2AMAPT | |
| SCHEMBL5086468 | 1.00 | THRB (0.40) | THRBMEN1HTTKMT2AMAPT | |
| SCHEMBL4523030 | 1.00 | THRB (0.40) | THRBMEN1HTTKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010039653-A1 | IONIC SILICONE HYDROGELS HAVING IMPROVED HYDROLYTIC STABILITY | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2010-04-08 | — | — | WO | disclosed |