SCHEMBL3345071

SCHEMBL3345071

C=CCO[C@H]1O[C@H](COCCCCC)[C@@H](OCCCCC)[C@H]1OCCCCC

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GJB2 P29033 4/20 0.41
SSTR1 P30872 3/20 0.39
SSTR2 P30874 3/20 0.39
SSTR4 P31391 3/20 0.39
SSTR3 P32745 3/20 0.39
SSTR5 P35346 3/20 0.39
FGF1 P05230 3/20 0.37
FGF2 P09038 3/20 0.37
VEGFA P15692 3/20 0.37
HPSE Q9Y251 3/20 0.37
TNF P01375 1/20 0.37
ALDH1A1 P00352 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
GBA1 P04062 1/20 0.34
ADRB2 P07550 1/20 0.32
TACR1 P25103 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3345069 1.00 GJB2 (0.41) GJB2SSTR1SSTR2SSTR4SSTR3
SCHEMBL12419813 0.95 GJB2 (0.40) GJB2SSTR1SSTR2SSTR4SSTR3
SCHEMBL12419788 0.95 GJB2 (0.40) GJB2SSTR1SSTR2SSTR4SSTR3
SCHEMBL14046678 0.90 GJB2 (0.38) GJB2SSTR1SSTR2SSTR4SSTR3
SCHEMBL5985701 0.87 GJB2 (0.46) GJB2SSTR1SSTR2SSTR4SSTR3
SCHEMBL11666504 0.87 GJB2 (0.46) GJB2SSTR1SSTR2SSTR4SSTR3
SCHEMBL5985705 0.87 GJB2 (0.46) GJB2SSTR1SSTR2SSTR4SSTR3
SCHEMBL11666500 0.87 GJB2 (0.46) GJB2SSTR1SSTR2SSTR4SSTR3
SCHEMBL14885872 0.86 GJB2 (0.44) GJB2SSTR1SSTR2SSTR4SSTR3
SCHEMBL19731780 0.86 GJB2 (0.44) GJB2SSTR1SSTR2SSTR4SSTR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101595117-B Method for production of furanose derivative API CORP 2014-01-22 CN disclosed
US-8394935-B2 Method for producing furanose derivative API CORPORATION (JP) 2013-03-12 US disclosed
US-8394935-B2 Method for producing furanose derivative API CORPORATION (JP) 2013-03-12 US disclosed
US-20100105890-A1 METHOD FOR PRODUCING FURANOSE DERIVATIVE API CORPORATION (JP) 2010-04-29 US disclosed
US-20100105890-A1 METHOD FOR PRODUCING FURANOSE DERIVATIVE API CORPORATION (JP) 2010-04-29 US disclosed
EP-2105445-A1 METHOD FOR PRODUCTION OF FURANOSE DERIVATIVE API Corporation (JP) 2009-09-30 EP disclosed
EP-2105445-A1 METHOD FOR PRODUCTION OF FURANOSE DERIVATIVE API Corporation (JP) 2009-09-30 EP disclosed
WO-2008069303-A1 METHOD FOR PRODUCTION OF FURANOSE DERIVATIVE API CORPORATION (JP) 2008-06-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100105890-A1 METHOD FOR PRODUCING FURANOSE DERIVATIVE DERA, ALDOA, DPYD GJB2 4735/4885SSTR1 2930/4885SSTR2 3130/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.