Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.70 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.70 |
| ▸ | MAOA | P21397 | 1/20 | 0.70 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.70 |
| ▸ | HTR2C | P28335 | 1/20 | 0.70 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.70 |
| ▸ | HTR2B | P41595 | 1/20 | 0.70 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.59 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.59 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.59 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.59 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 5/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2962505 | 0.90 | MAOA (0.84) | CYP1A2ADRA2AMAOASLC6A2HTR2C | |
| 2-Acetylaminofluorene SCHEMBL21114365 | 0.83 | CYP1A2 (1.00) | CYP1A2ADRA2AMAOASLC6A2HTR2C | |
| 2-Acetylaminofluorene SCHEMBL29364009 | 0.83 | CYP1A2 (1.00) | CYP1A2ADRA2AMAOASLC6A2HTR2C | |
| 2-Acetylaminofluorene SCHEMBL29829339 | 0.83 | CYP1A2 (1.00) | CYP1A2ADRA2AMAOASLC6A2HTR2C | |
| 2-Acetylaminofluorene SCHEMBL75140 | 0.83 | CYP1A2 (1.00) | CYP1A2ADRA2AMAOASLC6A2HTR2C | |
| SCHEMBL4380156 | 0.81 | MAOA (0.70) | CYP1A2ADRA2AMAOASLC6A2HTR2C | |
| 2-Acetylaminofluorene SCHEMBL6903872 | 0.81 | CYP1A2 (0.97) | CYP1A2ADRA2AMAOASLC6A2HTR2C | |
| 2-Acetylaminofluorene SCHEMBL5663545 | 0.78 | CYP1A2 (0.89) | CYP1A2ADRA2AMAOASLC6A2HTR2C | |
| SCHEMBL28178463 | 0.76 | CYP1A2 (0.88) | CYP1A2ADRA2AMAOASLC6A2HTR2C | |
| Water SCHEMBL8927845 | 0.76 | CYP1A2 (0.62) | CYP1A2ADRA2AMAOASLC6A2HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100162416-A1 | Multi-stage stem cell carcinogenesis | STEMLIFELINE, INC. (US) | 2010-06-24 | — | — | US | disclosed |
| WO-2010037134-A2 | MULTI-STAGE STEM CELL CARCINOGENESIS | STEMLIFELINE, INC. (US) | 2010-04-01 | — | — | WO | disclosed |