⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17842223 | 0.86 | ALDH1A1 (0.45) | — | |
| SCHEMBL4328355 | 0.77 | — | — | |
| SCHEMBL1116461 | 0.75 | — | — | |
| SCHEMBL15751130 | 0.75 | — | — | |
| SCHEMBL3345685 | 0.75 | — | — | |
| SCHEMBL2261089 | 0.75 | — | — | |
| SCHEMBL10802128 | 0.74 | — | — | |
| SCHEMBL11451535 | 0.73 | HCAR2 (0.45) | — | |
| Fumaric Acid SCHEMBL11884545 | 0.72 | HCAR2 (0.61) | — | |
| SCHEMBL7006989 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3914230-A1 | <SMALLCAPS/>? ? ?FUNCTIONALIZED LIPOSOMES FOR IMAGING MISFOLDED PROTEINS | Alzeca Biosciences, Llc (US) | 2021-12-01 | — | — | EP | claimed |
| CN-113543771-A | Functionalized liposomes for imaging misfolded proteins | 阿尔兹卡生物科学公司 | 2021-10-22 | — | — | CN | claimed |
| US-20200261605-A1 | FUNCTIONALIZED LIPOSOMES FOR IMAGING MISFOLDED PROTEINS | Alzeca Biosciences, LLC | 2020-08-20 | — | — | US | claimed |
| WO-2020154623-A1 | FUNCTIONALIZED LIPOSOMES FOR IMAGING MISFOLDED PROTEINS | Alzeca Biosciences, LLC (US) | 2020-07-30 | — | — | WO | claimed |
| US-20230136718-A1 | FUNCTIONALIZED LIPOSOMES FOR IMAGING MISFOLDED PROTEINS | Alzeca Biosciences, LLC (US) | 2023-05-04 | — | — | US | disclosed |
| EP-3914230-A1 | <SMALLCAPS/>? ? ?FUNCTIONALIZED LIPOSOMES FOR IMAGING MISFOLDED PROTEINS | Alzeca Biosciences, Llc (US) | 2021-12-01 | — | — | EP | disclosed |
| CN-113543771-A | Functionalized liposomes for imaging misfolded proteins | 阿尔兹卡生物科学公司 | 2021-10-22 | — | — | CN | disclosed |
| US-20200261605-A1 | FUNCTIONALIZED LIPOSOMES FOR IMAGING MISFOLDED PROTEINS | Alzeca Biosciences, LLC | 2020-08-20 | — | — | US | disclosed |
| WO-2020154623-A1 | FUNCTIONALIZED LIPOSOMES FOR IMAGING MISFOLDED PROTEINS | Alzeca Biosciences, LLC (US) | 2020-07-30 | — | — | WO | disclosed |
| US-8710246-B2 | Substituted thiophene pentamers | BIOCHROMIX NEWCO AB (SE) | 2014-04-29 | — | — | US | disclosed |
| US-20120157516-A1 | NOVEL THIOPHENE COMPOUNDS FOR USE IN THERAPY | BIOCHROMIX PHARMA AB | 2012-06-21 | — | — | US | disclosed |
| WO-2010044744-A1 | NOVEL THIOPHENE COMPOUNDS FOR IN VIVO IMAGING | BIOCHROMIX AB (SE) | 2010-04-22 | — | — | WO | disclosed |
| WO-2010044743-A1 | NOVEL THIOPHENE COMPOUNDS FOR USE IN THERAPHY | BIOCHROMIX PHARMA AB (SE) | 2010-04-22 | — | — | WO | disclosed |
| US-5935844-A | Porous cellulose carrier for immobilizing microorganisms to convert nitrogen compounds | BIOMATERIAL CO., LTD. (JP) | 1999-08-10 | — | — | US | disclosed |
| EP-0758680-A2 | Carrier for immobilizing microorganisms, and method for converting nitrogen compounds in a liquid using the same | Matsumura, Masatoshi (JP) | 1997-02-19 | — | — | EP | disclosed |