Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 10/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3347474 | 0.93 | SCD (0.71) | SCD | |
| SCHEMBL2316910 | 0.90 | SCD (0.73) | SCDALDH1A1HPGD | |
| SCHEMBL2313190 | 0.89 | SCD (1.00) | SCD | |
| SCHEMBL2311914 | 0.88 | SCD (0.76) | SCD | |
| SCHEMBL2318585 | 0.87 | SCD (0.84) | SCD | |
| SCHEMBL2315635 | 0.87 | SCD (0.75) | SCDALDH1A1HPGD | |
| SCHEMBL2318324 | 0.87 | SCD (0.75) | SCDALDH1A1HPGD | |
| SCHEMBL2314846 | 0.86 | SCD (0.85) | SCDALDH1A1HPGD | |
| SCHEMBL2319396 | 0.86 | SCD (0.73) | SCDALDH1A1HPGD | |
| SCHEMBL2319500 | 0.85 | SCD (0.78) | SCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010056230-A1 | 3-HYDROQUINAZOLIN-4-ONE DERIVATIVES FOR USE AS STEAROYL COA DESATURASE INHIBITORS | CV THERAPEUTICS, INC. (US) | 2010-05-20 | — | — | WO | disclosed |