Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 10/20 | 0.71 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3345815 | 0.93 | SCD (0.80) | SCD | |
| SCHEMBL2319700 | 0.90 | SCD (0.68) | SCDSMN1; SMN2 | |
| SCHEMBL2316986 | 0.89 | SCD (0.86) | SCDMAPTSLC2A1 | |
| SCHEMBL2317096 | 0.87 | SCD (0.69) | SCDMAPTMAPK1SMN1; SMN2SLC2A1 | |
| SCHEMBL2311790 | 0.84 | SCD (0.76) | SCDMAPT | |
| SCHEMBL2317091 | 0.83 | SCD (0.86) | SCDMAPT | |
| SCHEMBL2314537 | 0.83 | SCD (1.00) | SCDMAPT | |
| SCHEMBL2316910 | 0.83 | SCD (0.73) | SCDSMN1; SMN2 | |
| SCHEMBL2317479 | 0.82 | SCD (0.67) | SCDMAPTSLC2A1 | |
| SCHEMBL2313190 | 0.81 | SCD (1.00) | SCDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010056230-A1 | 3-HYDROQUINAZOLIN-4-ONE DERIVATIVES FOR USE AS STEAROYL COA DESATURASE INHIBITORS | CV THERAPEUTICS, INC. (US) | 2010-05-20 | — | — | WO | disclosed |