Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.37 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.37 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.37 |
| ▸ | HCAR1 | Q9BXC0 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | DAO | P14920 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL704132 | 0.82 | MAPKAPK2 (0.39) | MAPKAPK2RPS6KA3CSNK2A1PLK3HCAR1 | |
| SCHEMBL24156864 | 0.79 | MAPKAPK2 (0.37) | MAPKAPK2RPS6KA3CSNK2A1PLK3HCAR1 | |
| SCHEMBL30218628 | 0.79 | MAPKAPK2 (0.37) | MAPKAPK2RPS6KA3CSNK2A1PLK3HCAR1 | |
| SCHEMBL2825718 | 0.79 | DAO (0.47) | MAPKAPK2RPS6KA3CSNK2A1PLK3HCAR1 | |
| SCHEMBL30297078 | 0.75 | CA12 (0.50) | MAPKAPK2RPS6KA3CSNK2A1PLK3HCAR1 | |
| SCHEMBL30297088 | 0.75 | CA12 (0.50) | MAPKAPK2RPS6KA3CSNK2A1PLK3HCAR1 | |
| SCHEMBL2800776 | 0.71 | CA12 (0.50) | MAPKAPK2RPS6KA3CSNK2A1PLK3HCAR1 | |
| SCHEMBL2820360 | 0.71 | CA12 (0.58) | HCAR1ALDH1A1CA12CA9 | |
| SCHEMBL15231476 | 0.70 | CASP3 (0.37) | HCAR1DAO | |
| SCHEMBL22193197 | 0.68 | PDE3B (0.43) | MAPKAPK2RPS6KA3CSNK2A1PLK3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010045987-A1 | SUBSTITUTED (AZA) -1-METHYL-1H-QUIN0LIN-2-0NES AS ANTIBACTERIALS | GLAXO GROUP LIMITED (GB) | 2010-04-29 | — | — | WO | disclosed |
| WO-2010046388-A1 | SUBSTITUTED (AZA) -1-METHYL-1H-QUINOLIN-2-ONES AS ANTIBACTERIALS | GLAXO GROUP LIMITED (GB) | 2010-04-29 | — | — | WO | disclosed |
| WO-2010046388-A1 | SUBSTITUTED (AZA) -1-METHYL-1H-QUINOLIN-2-ONES AS ANTIBACTERIALS | GLAXO GROUP LIMITED (GB) | 2010-04-29 | — | — | WO | disclosed |