Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 18/20 | 0.63 |
| ▸ | ADORA1 | P30542 | 17/20 | 0.63 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3302521 | 0.86 | ADORA2A (0.62) | ADORA2AADORA1ADORA3 | |
| SCHEMBL3302518 | 0.86 | ADORA2A (0.62) | ADORA2AADORA1ADORA3 | |
| SCHEMBL3300399 | 0.84 | ADORA2A (0.64) | ADORA2AADORA1ADORA3 | |
| SCHEMBL3297795 | 0.78 | ADORA2A (0.65) | ADORA2AADORA1ADORA3 | |
| SCHEMBL13393922 | 0.77 | ADORA2A (0.64) | ADORA2AADORA1ADORA3 | |
| SCHEMBL3302826 | 0.77 | ADORA2A (1.00) | ADORA2AADORA1 | |
| SCHEMBL3351568 | 0.77 | ADORA2A (0.75) | ADORA2AADORA1ADORA3 | |
| SCHEMBL3309309 | 0.77 | ADORA2A (1.00) | ADORA2AADORA1ADORA3 | |
| SCHEMBL3307751 | 0.77 | ADORA2A (0.82) | ADORA2AADORA1ADORA3 | |
| SCHEMBL3303782 | 0.76 | ADORA2A (1.00) | ADORA2AADORA1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010045013-A1 | PHENYL SUBSTITUTED THIENO [2,3-D] PYRIMIDINES AND THEIR USE AS ADENOSINE A2A RECEPTOR ANTAGONISTS | JANSSEN PHARMACEUTICA NV (BE) | 2010-04-22 | — | — | WO | disclosed |