⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16264292 | 0.81 | — | — | |
| SCHEMBL7373104 | 0.77 | — | — | |
| SCHEMBL8201407 | 0.77 | — | — | |
| SCHEMBL1751779 | 0.76 | — | — | |
| SCHEMBL17963058 | 0.74 | — | — | |
| SCHEMBL5709793 | 0.70 | HTT (0.32) | — | |
| SCHEMBL3341420 | 0.69 | — | — | |
| SCHEMBL11103519 | 0.67 | — | — | |
| SCHEMBL23049158 | 0.66 | ALOX15 (0.38) | — | |
| SCHEMBL8469471 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2127650-B1 | Carbapenem antibacterials with gram-negative activity and processes for their preparation | FOB SYNTHESIS INC (US) | 2018-12-05 | — | — | EP | disclosed |
| US-8557979-B2 | Carbapenem antibacterials with gram-negative activity and processes for their preparation | FOB SYNTHESIS, INC. (US) | 2013-10-15 | — | — | US | disclosed |
| US-20120296084-A1 | Carbapenem Antibacterials with Gram-Negative Activity and Processes for Their Preparation | FOB SYNTHESIS, INC. (US) | 2012-11-22 | — | — | US | disclosed |
| US-8232268-B2 | Carbapenem antibacterials with gram-negative activity and processes for their preparation | FOB SYNTHESIS, INC. (US) | 2012-07-31 | — | — | US | disclosed |
| US-20100160284-A1 | CARBAPENEM ANTIBACTERIALS WITH GRAM-NEGATIVE ACTIVITY AND PROCESSES FOR THEIR PREPARATION | FOB SYNTHESIS, INC., (US) | 2010-06-24 | — | — | US | disclosed |
| US-7683049-B2 | Carbapenem antibacterials with gram-negative activity and processes for their preparation | FOB SYNTHESIS, INC. (US) | 2010-03-23 | — | — | US | disclosed |
| EP-2127650-A2 | Carbapenem antibacterials with gram-negative activity and processes for their preparation | FOB Synthesis, Inc. (US) | 2009-12-02 | — | — | EP | disclosed |
| EP-1765326-A4 | CARBAPENEM ANTIBACTERIALS WITH GRAM-NEGATIVE ACTIVITY AND PROCESSES FOR THEIR PREPARATION | FOB SYNTHESIS INC (US) | 2009-05-13 | — | — | EP | disclosed |
| EP-1765326-A1 | CARBAPENEM ANTIBACTERIALS WITH GRAM-NEGATIVE ACTIVITY AND PROCESSES FOR THEIR PREPARATION | FOB Synthesis, Inc. (US) | 2007-03-28 | — | — | EP | disclosed |
| US-20060069081-A1 | Carbapenem antibacterials with gram-negative activity and processes for their preparation | CHOI, WOO-BAEG, DR. | 2006-03-30 | — | — | US | disclosed |
| WO-2005123066-A1 | CARBAPENEM ANTIBACTERIALS WITH GRAM-NEGATIVE ACTIVITY AND PROCESSES FOR THEIR PREPARATION | FOB SYNTHESIS, INC. (US) | 2005-12-29 | — | — | WO | disclosed |