Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRPF1 | P55201 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 8/20 | 0.32 |
| ▸ | PRKDC | P78527 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 2/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.30 |
| ▸ | ATR | Q13535 | 1/20 | 0.30 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13424820 | 0.82 | DAO (0.36) | PIK3CAALDH1A1 | |
| SCHEMBL3374251 | 0.81 | HSD17B13 (0.33) | PIK3CAPRKDC | |
| SCHEMBL3375679 | 0.81 | L3MBTL1 (0.33) | PIK3CAALDH1A1 | |
| SCHEMBL30236914 | 0.81 | L3MBTL1 (0.33) | PIK3CAALDH1A1 | |
| SCHEMBL18544283 | 0.78 | CYP1A2 (0.37) | PIK3CAPRKDCALDH1A1 | |
| SCHEMBL13425000 | 0.78 | USP2 (0.33) | PIK3CADPP4ALDH1A1 | |
| SCHEMBL3376345 | 0.78 | MEN1 (0.32) | PIK3CAALDH1A1 | |
| SCHEMBL3374526 | 0.77 | PIK3CA (0.31) | PIK3CA | |
| SCHEMBL3375288 | 0.77 | DPP4 (0.31) | PIK3CADPP4 | |
| SCHEMBL3378607 | 0.77 | KCNH2 (0.31) | PIK3CAATMATRDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010045987-A1 | SUBSTITUTED (AZA) -1-METHYL-1H-QUIN0LIN-2-0NES AS ANTIBACTERIALS | GLAXO GROUP LIMITED (GB) | 2010-04-29 | — | — | WO | disclosed |
| WO-2010046388-A1 | SUBSTITUTED (AZA) -1-METHYL-1H-QUINOLIN-2-ONES AS ANTIBACTERIALS | GLAXO GROUP LIMITED (GB) | 2010-04-29 | — | — | WO | disclosed |