Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 1/20 | 0.41 |
| ▸ | SKP1 | P63208 | 1/20 | 0.41 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7835874 | 0.79 | CKS1B (0.37) | CKS1BSKP1SKP2NPSR1IDO1 | |
| SCHEMBL6682212 | 0.78 | NQO2 (0.53) | NPSR1IDO1ALDH1A1HTTKMT2A | |
| SCHEMBL30408678 | 0.78 | NQO2 (0.53) | NPSR1IDO1ALDH1A1HTTKMT2A | |
| SCHEMBL14476195 | 0.77 | MEN1 (0.52) | CKS1BSKP1SKP2MALT1ALDH1A1 | |
| SCHEMBL17563564 | 0.76 | SNCA (0.42) | CKS1BSKP1SKP2ALDH1A1KMT2A | |
| SCHEMBL29655446 | 0.76 | NPC1 (0.59) | MALT1ALDH1A1HTTBCHEMAPT | |
| SCHEMBL2982740 | 0.76 | NPC1 (0.59) | MALT1ALDH1A1HTTBCHEMAPT | |
| SCHEMBL4371396 | 0.76 | KMT2A (0.45) | ALDH1A1HTTCA1CA2KMT2A | |
| SCHEMBL10199951 | 0.75 | NPSR1 (0.45) | NPSR1ALDH1A1HTTMAPTKMT2A | |
| SCHEMBL890852 | 0.75 | BCHE (0.40) | IDO1ALDH1A1BCHEMAPTCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010053757-A1 | 2 -OXOQUINOXALIN BLOCKERS OF THE LATE SODIUM CHANNEL | GILEAD PALO ALTO, INC. (US) | 2010-05-14 | — | — | WO | disclosed |