Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 2/20 | 0.51 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.51 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 6/20 | 0.39 |
| ▸ | KDM6B | O15054 | 4/20 | 0.39 |
| ▸ | GCK | P35557 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.37 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.36 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3345812 | 0.86 | PIM1 (0.43) | PIM1PIM2KDRCNR2SLC2A1 | |
| SCHEMBL3448577 | 0.84 | TSHR (0.44) | PIM1PIM2CNR2MEN1KMT2A | |
| SCHEMBL3451828 | 0.79 | CNR2 (0.44) | CNR2KMT2A | |
| SCHEMBL31481588 | 0.77 | CNR2 (0.43) | CNR2KDM4CKMT2ASORT1 | |
| SCHEMBL1505065 | 0.76 | CNR2 (0.48) | CNR2KMT2ASORT1 | |
| SCHEMBL18584645 | 0.75 | FOLH1 (0.49) | MEN1KMT2ASLC16A3 | |
| SCHEMBL6362662 | 0.74 | HSD17B10 (0.50) | CNR2KMT2A | |
| SCHEMBL3376837 | 0.73 | KDM4E (0.55) | MEN1KMT2A | |
| SCHEMBL21512633 | 0.73 | KDM4E (0.46) | CNR2MEN1KMT2A | |
| SCHEMBL4014183 | 0.73 | PTGER4 (0.44) | KDM4CMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010038081-A2 | HETEROCYCLIC DERIVATIVES AND METHODS OF USE THEREOF | ASTRAZENECA AB (SE) | 2010-04-08 | — | — | WO | disclosed |