Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | LCK | P06239 | 1/20 | 0.51 |
| ▸ | FYN | P06241 | 1/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | AHR | P35869 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 6/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | TYMS | P04818 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9576677 | 0.78 | HPRT1 (0.50) | ALDH1A1CYP1A2MAPTLCKFYN | |
| SCHEMBL8359592 | 0.76 | HPGD (0.51) | ALDH1A1CYP1A2MAPTHPGDHSD17B10 | |
| SCHEMBL30286397 | 0.73 | ALDH1A1 (0.55) | ALDH1A1CYP1A2MAPTLCKFYN | |
| SCHEMBL597682 | 0.73 | ALDH1A1 (0.55) | ALDH1A1CYP1A2MAPTLCKFYN | |
| SCHEMBL31235725 | 0.72 | HPRT1 (0.56) | ALDH1A1CYP1A2MAPTLCKFYN | |
| SCHEMBL27976174 | 0.72 | HPRT1 (0.47) | ALDH1A1CYP1A2MAPTLCKFYN | |
| SCHEMBL27463276 | 0.72 | HPRT1 (0.47) | ALDH1A1CYP1A2MAPTLCKFYN | |
| SCHEMBL531158 | 0.70 | CYP1A2 (0.42) | ALDH1A1CYP1A2MAPTLCKFYN | |
| SCHEMBL9181184 | 0.69 | KDM4E (0.49) | ALDH1A1CYP1A2MAPTHPGDHSD17B10 | |
| SCHEMBL7413330 | 0.69 | BRD4 (0.48) | ALDH1A1CYP1A2MAPTHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100162416-A1 | Multi-stage stem cell carcinogenesis | STEMLIFELINE, INC. (US) | 2010-06-24 | — | — | US | disclosed |
| WO-2010037134-A2 | MULTI-STAGE STEM CELL CARCINOGENESIS | STEMLIFELINE, INC. (US) | 2010-04-01 | — | — | WO | disclosed |