Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 1/20 | 0.52 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.52 |
| ▸ | ITGAL | P20701 | 1/20 | 0.52 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | CA12 | O43570 | 3/20 | 0.49 |
| ▸ | CA1 | P00915 | 3/20 | 0.49 |
| ▸ | CA2 | P00918 | 3/20 | 0.49 |
| ▸ | CA3 | P07451 | 3/20 | 0.49 |
| ▸ | CA4 | P22748 | 3/20 | 0.49 |
| ▸ | CA6 | P23280 | 3/20 | 0.49 |
| ▸ | CA5A | P35218 | 3/20 | 0.49 |
| ▸ | CA7 | P43166 | 3/20 | 0.49 |
| ▸ | CA9 | Q16790 | 3/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.49 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.49 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2476912 | 1.00 | ITGB2 (0.52) | ITGB2ICAM1ITGALSLC22A12KDM4E | |
| SCHEMBL8153860 | 0.85 | KDM4E (0.56) | SLC22A12KDM4EHSD17B10ALDH1A1MAPK1 | |
| SCHEMBL8153863 | 0.85 | KDM4E (0.56) | SLC22A12KDM4EHSD17B10ALDH1A1MAPK1 | |
| SCHEMBL6010547 | 0.82 | KDM4E (0.64) | SLC22A12KDM4EHSD17B10ALDH1A1MAPK1 | |
| SCHEMBL9832961 | 0.82 | AR (0.43) | ITGB2ICAM1ITGALSLC22A12HDAC3 | |
| SCHEMBL9555529 | 0.82 | AR (0.43) | ITGB2ICAM1ITGALSLC22A12HDAC3 | |
| SCHEMBL1338627 | 0.81 | SLC22A12 (0.49) | SLC22A12KDM4EHSD17B10ALDH1A1MAPK1 | |
| SCHEMBL1338625 | 0.81 | SLC22A12 (0.49) | SLC22A12KDM4EHSD17B10ALDH1A1MAPK1 | |
| SCHEMBL6411641 | 0.81 | SLC22A12 (0.49) | SLC22A12KDM4EHSD17B10ALDH1A1MAPK1 | |
| SCHEMBL6411645 | 0.81 | SLC22A12 (0.49) | SLC22A12KDM4EHSD17B10ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100160369-A1 | S1P1 Agonists and Methods of Making And Using | EXELIXIS, INC. (US) | 2010-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100160369-A1 | S1P1 Agonists and Methods of Making And Using | S1PR1, S1PR5, S1PR3 | ITGB2 1141/4885ICAM1 1102/4885ITGAL 1074/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.