SCHEMBL334682

SCHEMBL334682

O=C(NCC(O)CO)OCc1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
HTT P42858 1/20 0.54
ALDH1A1 P00352 1/20 0.50
CTSK P43235 4/20 0.49
CTSS P25774 4/20 0.49
CTSL P07711 3/20 0.49
CTSB P07858 2/20 0.49
SYK P43405 1/20 0.49
SLC6A2 P23975 1/20 0.49
SLC6A3 Q01959 1/20 0.49
KMT2A Q03164 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
SLC1A3 P43003 1/20 0.48
SLC1A1 P43005 1/20 0.48
TGM2 P21980 1/20 0.48
CTRB1 P17538 2/20 0.48
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1568538 1.00 LMNA (0.56) LMNASMN1; SMN2HTTALDH1A1CTSK
SCHEMBL1569295 1.00 LMNA (0.56) LMNASMN1; SMN2HTTALDH1A1CTSK
SCHEMBL5019087 0.92 LMNA (0.61) LMNASMN1; SMN2HTTALDH1A1CTSS
SCHEMBL16691249 0.88 LMNA (0.54) LMNASMN1; SMN2HTTALDH1A1CTSS
SCHEMBL4923251 0.88 LMNA (0.54) LMNASMN1; SMN2HTTALDH1A1CTSS
SCHEMBL16691163 0.88 LMNA (0.54) LMNASMN1; SMN2HTTALDH1A1CTSS
SCHEMBL6422499 0.88 HTT (0.56) LMNASMN1; SMN2HTTKMT2ASLC1A3
SCHEMBL12067897 0.88 LMNA (0.56) LMNASMN1; SMN2HTTALDH1A1CTSK
SCHEMBL6647168 0.88 LMNA (0.56) LMNASMN1; SMN2HTTALDH1A1CTSK
SCHEMBL24326102 0.86 LMNA (0.55) LMNASMN1; SMN2HTTALDH1A1CTSS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4642773-A1 NEW BENZIMIDAZOLE DERIVATIVES F. Hoffmann-La Roche AG (CH) 2025-11-05 EP disclosed
WO-2024141444-A1 NEW BENZIMIDAZOLE DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2024-07-04 WO disclosed
CN-117881661-A Condensed heterocyclic derivative 杨森科学爱尔兰无限公司 2024-04-12 CN disclosed
US-20220081737-A1 POND REACTOR FOR RECOVERY OF METALS CYCAD GROUP, LLC 2022-03-17 US disclosed
US-20210340025-A1 Compositions and Methods for Purification of Metals from Steel Making Waste Streams CYCAD GROUP, LLC 2021-11-04 US disclosed
CN-113165897-A Compositions and methods for purifying metals from steelmaking waste streams 里克希维亚有限公司 2021-07-23 CN disclosed
WO-2020131958-A1 POND REACTOR FOR RECOVERY OF METALS Lixivia, Inc. (US) 2020-06-25 WO disclosed
US-20180223392-A1 COMPOSITIONS AND METHODS FOR RECOVERY OF ALKALINE METALS CYCAD GROUP, LLC 2018-08-09 US disclosed
US-20160252518-A1 QUATERNARY AMINE CONTAINING ISOBARIC TAG FOR QUANTITATIVE GLYCAN PROFILING THE JOHNS HOPKINS UNIVERSITY 2016-09-01 US disclosed
WO-2015011252-A1 PYRIMIDINE-PYRIDINONE SERINE/THREONINE KINASE INHIBITORS F. HOFFMANN-LA ROCHE AG (CH) 2015-01-29 WO disclosed
WO-1989010751-A1 FUNCTIONALIZED PEPTIDYL AMINODIOLS AND -TRIOLS ABBOTT LABORATORIES (US) 1989-11-16 WO disclosed
WO-1989010752-A1 RETROVIRAL PROTEASE INHIBITORS ABBOTT LABORATORIES (US) 1989-11-16 WO disclosed
EP-0341602-A2 Renin-inhibiting functionalized peptidyl aminodiols and - triols ABBOTT LABORATORIES (US) 1989-11-15 EP disclosed
US-4857507-A HYPOTENSIVE AGENT ABBOTT LABORATORIES (US) 1989-08-15 US disclosed
US-4837204-A RENIN INHIBITORS; HYPOTENSIVE AGENTS ABBOTT LABORATORIES (US) 1989-06-06 US disclosed
US-4826815-A HYPOTENSIVE ABBOTT LABORATORIES (US) 1989-05-02 US disclosed
EP-0307837-A2 Renin-inhibiting peptidyl heterocycles ABBOTT LABORATORIES (US) 1989-03-22 EP disclosed
EP-0258289-A1 PEPTIDE ANALOGS ABBOTT LABORATORIES (US) 1988-03-09 EP disclosed
WO-1987004349-A1 PEPTIDE ANALOGS DELLARIA JOSEPH 1987-07-30 WO disclosed
EP-0230266-A2 Functionalized peptidyl aminodiols and -triols ABBOTT LABORATORIES (US) 1987-07-29 EP disclosed