SCHEMBL3347063

SCHEMBL3347063

CC1=CC(O)/C(=N/Cc2ccccn2)C=C1

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.35
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
HRH3 Q9Y5N1 1/20 0.33
ALDH1A1 P00352 3/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
SYK P43405 1/20 0.33
CYP1A2 P05177 1/20 0.33
TSHR P16473 1/20 0.33
LMNA P02545 2/20 0.33
TAAR1 Q96RJ0 1/20 0.33
ALOX15 P16050 1/20 0.33
HRH1 P35367 1/20 0.33
HTT P42858 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3347066 1.00 SMN1; SMN2 (0.35) SMN1; SMN2NPC1RAB9AHRH3ALDH1A1
SCHEMBL3343580 0.80 SMN1; SMN2 (0.34) SMN1; SMN2NPC1RAB9AHRH3ALDH1A1
SCHEMBL3341790 0.78 SMN1; SMN2 (0.37) SMN1; SMN2NPC1RAB9AHRH3ALDH1A1
SCHEMBL3342834 0.71 SMN1; SMN2 (0.34) SMN1; SMN2NPC1RAB9AALDH1A1L3MBTL1
SCHEMBL3342829 0.71 SMN1; SMN2 (0.34) SMN1; SMN2NPC1RAB9AALDH1A1L3MBTL1
SCHEMBL3342439 0.71 ALDH1A1 (0.33) SMN1; SMN2NPC1RAB9AHRH3ALDH1A1
SCHEMBL3342452 0.71 ALDH1A1 (0.33) SMN1; SMN2NPC1RAB9AHRH3ALDH1A1
SCHEMBL3347448 0.69 SMN1; SMN2 (0.33) SMN1; SMN2NPC1RAB9AALDH1A1L3MBTL1
SCHEMBL3347440 0.69 SMN1; SMN2 (0.33) SMN1; SMN2NPC1RAB9AALDH1A1L3MBTL1
SCHEMBL3342429 0.67 KMT2A (0.35) SMN1; SMN2NPC1RAB9AALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2010550-B1 POLYMERISATION OF ETHYLENE AND ALPHA-OLEFINS WITH PYRIDINO-IMINOPHENOL COMPLEXES TOTAL RES & TECHNOLOGY FELUY (BE) 2013-06-19 EP disclosed
US-8399582-B2 Polymerisation of ethylene and alpha-olefins with pyridino-iminophenol complexes TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2013-03-19 US disclosed
US-20100160583-A1 Polymerisation of Ethylene and Alpha-Olefins with Pyridino-Iminophenol Complexes TOTAL PETROCHEMICALS RESEARCH FEULY (BE) 2010-06-24 US disclosed
EP-1849791-A1 Polymerisation of ethylene and alpha-olefins with pyridino-iminophenol complexes TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2007-10-31 EP disclosed