Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 13/20 | 0.60 |
| ▸ | NPC1 | O15118 | 12/20 | 0.60 |
| ▸ | MAPT | P10636 | 8/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | PKM | P14618 | 2/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.60 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 6/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 11/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 3/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | USP2 | O75604 | 3/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3347093 | 0.88 | SMN1; SMN2 (0.67) | RAB9ANPC1MAPTKMT2APKM | |
| SCHEMBL3346405 | 0.86 | NPC1 (0.67) | RAB9ANPC1MAPTKMT2ANPSR1 | |
| SCHEMBL3346882 | 0.83 | SMN1; SMN2 (0.66) | RAB9ANPC1MAPTKMT2APKM | |
| SCHEMBL14790064 | 0.82 | NPC1 (0.68) | RAB9ANPC1MAPTKMT2APKM | |
| SCHEMBL2485970 | 0.82 | RAB9A (0.64) | RAB9ANPC1MAPTKMT2APKM | |
| Bromide SCHEMBL3351950 | 0.82 | MAPT (0.62) | RAB9ANPC1MAPTKMT2APKM | |
| SCHEMBL12199474 | 0.80 | RAB9A (0.62) | RAB9ANPC1MAPTKMT2APKM | |
| SCHEMBL3347250 | 0.80 | RAB9A (0.67) | RAB9ANPC1MAPTKMT2AOPRK1 | |
| SCHEMBL2483529 | 0.79 | RAB9A (0.61) | RAB9ANPC1MAPTKMT2APKM | |
| SCHEMBL2482559 | 0.79 | MAPT (0.62) | RAB9ANPC1MAPTKMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010066357-A1 | BENZOTHIAZOLE AMIDES FOR DETECTION OF AMYLOID BETA | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-06-17 | — | — | WO | disclosed |