Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 16/20 | 0.51 |
| ▸ | HTR2A | P28223 | 15/20 | 0.51 |
| ▸ | HTR2B | P41595 | 15/20 | 0.51 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.34 |
| ▸ | PKLR | P30613 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9947932 | 0.89 | HTR2C (0.46) | HTR2CHTR2AHTR2B | |
| SCHEMBL2573385 | 0.83 | HTR2C (0.73) | HTR2CHTR2AHTR2B | |
| SCHEMBL2573429 | 0.81 | HTR2C (0.50) | HTR2CHTR2AHTR2B | |
| SCHEMBL10218414 | 0.79 | HTR2C (0.57) | HTR2CHTR2AHTR2B | |
| SCHEMBL9947820 | 0.78 | MEN1 (0.54) | HTR2CHTR2AHTR2B | |
| SCHEMBL10216877 | 0.76 | HTR2C (0.62) | HTR2CHTR2AHTR2B | |
| SCHEMBL2570503 | 0.73 | HTR2C (0.58) | HTR2CHTR2AHTR2B | |
| SCHEMBL2569906 | 0.73 | HTR2C (0.44) | HTR2CHTR2AHTR2B | |
| SCHEMBL2569904 | 0.73 | HTR2C (0.44) | HTR2CHTR2AHTR2B | |
| SCHEMBL2571912 | 0.73 | MEN1 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010060952-A1 | 6,7,8,9-TETRAHYDRO-5H-1,4,7,10A-TETRAAZA-CYCLOHEPT[F]INDENE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS, THEIR USE AND PROCESSES FOR PREPARING THEM | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-06-03 | — | — | WO | disclosed |